白血病人化疗后实施保护性隔离预防感染的效果评价  

The Efficacy Evaluation of the Protective Isolation on Infection after Chemotherapy for Leukemic Patients

作　　者：张家会[1] 鄢丽霞 吴秀[1] 李晓蓉[1] 周学敏[1] 青玉凤[2] 

机构地区：[1]简阳市人民医院血液科,四川简阳641400 [2]川北医学院附属医院风湿血液科,四川南充637000

出　　处：《现代生物医学进展》2014年第17期3338-3340,3400,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨白血病患者化疗后实施保护性隔离对预防感染的临床效果。方法:2011年7月至2013年7月期间,我院诊治的80例白血病患者,随机分为对照组(常规预防感染措施)和观察组(保护性隔离措施),每组各40例,均于骨髓抑制期开始,给予相应的预防性感染措施,对两组临床疗效、中性粒细胞恢复正常时间,以及各项感染发生率,进行观察和比较。结果:与对照组相比,观察组有效率明显升高,中性粒细胞恢复正常时间明显缩短,发热、口腔溃疡、上呼吸道感染、肺炎、败血症等各项感染发生率明显降低,差异有统计学意义(P<0.05)。结论:白血病患者化疗后实施保护性隔离措施,能够明显降低感染发生率,值得临床推广。Objective： To study the clinical efficacy of the protective isolation on infection after chemotherapy for leukemic patients. Methods： The 80 leukemic patients in our hospital during the period from July 2011 to July 2013 were randomized into the control group （routine proventive measures） and the observation group （protective isolation measures）, 40 patients per group. The relative proventive infection measures were done after chemotherapy immediately in the two groups. The clinical efficacy, the neutrophil recovery time, and the incidence of all kinds of infections in the two groups were observed and compared. Results： Compared with the control group, the effective rate was significantly increased, while the neutrophil recovery time was obviously reduced, the incidences of all kinds of infections such as fever, oral ulcer, upper respiratory tract infection, pneumonia, and septicemia significantly decreased with statistical difference （P 〈0.05）. Conclusion： The protective isolation on infection after chemotherapy for leukemic patients can significantly reduce the incidence of infection and is worthy of clinical promotion.

关 键 词：白血病 化疗 保护性隔离 预防感染 

分 类 号：R733.7[医药卫生—肿瘤]