急性胰腺炎血糖、血清胰岛素及C肽水平检测意义  

Detection of blood sugar, serum insulin and peptide C in acute pancreatitis

作　　者：严爱芬[1] 周蒙滔[2] 吴坚敏[1] 

机构地区：[1]浙江省余姚市人民医院检验科,浙江余姚315400 [2]温州医学院附属第一医院普外科,浙江温州325035

出　　处：《中国现代医生》2014年第16期69-72,共4页China Modern Doctor

基　　金：国家自然科学基金(81070372)

摘　　要：目的探讨急性胰腺炎患者血糖、血清胰岛素、C肽的水平变化。方法选择急性胰腺炎患者98例为研究对象,根据患者的严重程度分为轻型组、重症Ⅰ级组和重症Ⅱ级组,并选择健康体检者30例为对照组。测量急性胰腺炎患者不同时间点以及健康对照组血糖水平、血清胰岛素以及C肽水平。结果入院时三组血糖水平显著高于对照组,胰岛素和C肽水平也显著高于对照组(P<0.01)。急性胰腺炎患者中,重症Ⅱ级的血糖、胰岛素、C肽水平最高(P<0.01)。急性胰腺炎患者胰岛素和C肽水平均显著下降,而重症患者显著低于正常对照组(P<0.01)。结论胰腺炎患者血糖显著升高,并且病情越重则血糖升高越明显。发病后6 h内,患胰岛素和C肽水平都会升高,发病后次日,胰岛素水平和C肽下降,并且病情越重则下降越明显。Objective To discuss significance of level change of blood sugar, serum insulin and peptide C in acute pancreatitis. Methods Selected 98 cases with acute pancreatitis were divided into mild group, severe Ⅰ group and severe Ⅱ group according to severity. Thirty healthy controls were selected as control group. Blood sugar, serum insulin and peptide C were detected. Results On admission, levels of blood sugar, serum insulin and peptide C in mild group, severe Ⅰ group and severe Ⅱ group were higher than control group （P〈0.01）. Levels of blood sugar, serum insulin and peptide C in severe Ⅱ group were higherst （P〈0.01）. Then, Levels of blood sugar, serum insulin and peptide C in three groups decreased, and that of severe groups were apparently lower than control group （P〈0.01）. Conclusion Blood sugar level increases in acute pancreatitis, and the more of severity, the higher of the level. In 6h after attack, serum insulin and peptide C increase, and then decrease next day of attack. The more of severity, the more of decrease are.

关 键 词：急性胰腺炎 血清胰岛素 C肽 血糖 

分 类 号：R576[医药卫生—消化系统]