血清铜锌硒与卵巢癌关系的研究  

Studies on Serum Cu,Zn and Se in Patients with Ovarian Cancer

作　　者：林峰[1] 吴芳斌 孙国平[1] 

机构地区：[1]安徽医科大学第一附属医院,合肥230022 [2]桐城市中医院肿瘤科,桐城231402

出　　处：《微量元素与健康研究》2001年第1期29-30,共2页Studies of Trace Elements and Health

摘　　要：对 40例卵巢癌患者进行血清铜、锌、硒及铜 /锌比值测定 ,并以 48例健康成年女性为对照。测定结果进行单因素分析和非条件 Logistic多因素分析。单因素分析结果表明 ,卵巢癌患者血清锌、硒低于正常组 ,铜 /锌比值升高 ,而血清铜无显著差异 ;有负荷患者铜 /锌比值明显高于无负荷患者 ,而血清锌、硒无显著差异。回归多因素分析表明 ,硒、锌是卵巢癌发病的保护因素 ,揭示锌、硒在卵巢癌预防及辅助治疗上均有一定价值。The concentrations of serum copper,zinc,selenium and copper/zinc ratio in 40 patients with ovarian cancer were determined and analysed by t test and non-condition logistic regression factors.The results showed that serum copper concentration and copper/zinc ratio in patients increased while serum zinc and selenium concentration decreased.There is a significant correlation between the incremental concentration of serum copper and copper/zinc ratio and the load of the disease.The result indicated that serum copper/zinc ratio would be of great value in supervising the change of patients with ovarian cancer.The analytical result of non-condition multiple factors indicated that serum zinc and selenium concentration may be protective factors of ovarian cancer.

关 键 词：血清铜 血清锌 血清硒 卵巢癌 相关性 铜/锌比值 

分 类 号：R737.31[医药卫生—肿瘤]