中晚期原发性肝癌的预后因素分析  

Analysis of Prognostic Factors of Advanved Hepatocellular Carvinoma

作　　者：周孟强[1] 王万胜 段文杰[3] 戴涤新[1] 孙喜斌[3] 

机构地区：[1]河南省肿瘤医院,郑州450003 [2]禹州市人民医院 [3]河南省肿瘤研究所

出　　处：《河南职工医学院学报》2001年第1期16-17,共2页Journal of Henan Medical College For Staff and Workers

摘　　要：目的 :探讨有关临床因素对中晚期肝癌预后的影响。方法 :收集 35 0例原发性肝癌患者的诊治信息 ,应用Kaplan -Meier法和COX模型对一些临床因素进行生存及预后因素分析。 结果 :失访率 2 8.6 % ,全组 1,3,5年生存率分别为 38% ,12 .1% ,6 .9%。多因素COX模型分析显示影响中晚期肝癌的临床预后因素为 :临床分期、治疗方法及肝内播散等。结论 :临床分期、治疗方法等临床因素可作为判断中晚期肝癌预后的指标 。Objective:To explore influence of some clinical factors on prognosis of advanved hepatovellular carcinoma.Methods:350 cases with hepatocellular carcinoma were selected to sutdy.using Kaplem-Meier's methoed and COX model,analysis of susrvival and prognostic factors were performed to some clinical factors.Ressults:The result showed that rate of loss to follow-up was 28.6% and the over-all survival rates were 38% at one year 12.1% at 3 year and 6.9%.at 5 years separately.The result of multivariae COX model analysis showed that the significant prognostic factors were clinical stage,methods of treatment and spread in liver,Conclusion:Clinical factors of clinical stage and methods of treatment et al were the indexes for indentifing the prognosis of hepatocellular caroinoma.\;

关 键 词：原发性肝癌 预后因素 COX模型 

分 类 号：R735.7[医药卫生—肿瘤]