太极通天液与钙离子拮抗剂防治偏头痛疗效对照研究  

TAIJI TONGTIAN ORAL SOLUTION VERSUS CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF MIGRAINE

作　　者：项建平[1] 薛彦忠[1] 聂成福[1] 

机构地区：[1]山东省临沂市沂水中心医院,山东276400

出　　处：《中国疼痛医学杂志》2001年第1期19-21,共3页Chinese Journal of Pain Medicine

摘　　要：目的 :对照观察太极通天液与钙离子拮抗剂防治偏头痛的临床疗效。方法 :将345例偏头痛患者随机分为三组 :太极通天液组 (n =1 1 7)、钙离子拮抗剂组 (n =1 1 0 )和联合用药组 (n =1 1 8)。根据患者治疗前后头痛发作次数、头痛程度、头痛持续时间和伴随症状的变化进行疗效评定 ,观察期为 3个月。结果 :(1 )钙离子拮抗剂防治偏头痛的显效率为 45.5% ,总有效率为 80 .0 % ,与文献报告相近似 ;(2 )太极通天液显效率为 46.2 % ,总有效率 82 .9% ,与钙离子拮抗剂相似 ;(3)联合用药组显效率 63.6% ,显著高于单独用药组 (P <0 .0 1 ) ,总有效率 85.6 % ,与单独用药组无显著差异。结论 :太极通天液是一种有效的偏头痛防治药物 ;Objective:To compare the efficacies of Taiji Tongtian(TJTT) Oral Solution with Calcium channel antagonists for the treatment of migraine. Methods: 345 patients were randomly divided into three groups: Group A(n=117), treated with TJTT Oral Solution; Group B(n=110), treated with Calcium channel antagonists and Group C(n=118 ) treated with both drugs. The efficacy was assessed on the basis of the following variables: frequency of migraine attack, intensity of headache, duration of attacks and accompanying syndromes. The duration of observation was 3 months. Results: (1) The marked effective rate and total effective rate for group A were 45.5% and 80.0% respectively, which were similar with the results published in the literature.(2) The corresponding values for group B were 46.2% and 82.9%, not significantly different from that of group A. (3) The group C showed a marked effective rate of 63.6%, which was significantly higher ( P <0.01) than the corresponding values in group A and B, although the total effective rate (85.6%) remained in the same magnitude. Conclution:TJTT Oral Solution is an effective drug for the treatment of migraine. It can be used in combination with Calcium channel antagonists to increase the therapeutic efficacy.

关 键 词：太极通天液 偏头痛 钙离子拮抗剂 联合药物治疗 

分 类 号：R747.2[医药卫生—神经病学与精神病学]