穴位埋线治疗单纯性肥胖随机对照临床研究文献Meta分析  

Clinical randomized controlled trials of acupoint catgut-embedding for simple obesity:a Meta-analysis

作　　者：廖建琼[1] 宋翔[1] 陈莹[1] 梁丽嫦[1] 王升旭[1] 

机构地区：[1]南方医科大学中医药学院针灸教研室,广东广州510515

出　　处：《中国针灸》2014年第6期621-626,共6页Chinese Acupuncture & Moxibustion

摘　　要：系统分析穴位埋线治疗单纯性肥胖的临床疗效,为临床治疗及开展相关研究提供参考和帮助。通过检索中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、维普期刊数据库(VIP)、万方数据库、Pubmed、Springer、Medline数据库,收集2009年1月至2013年7月穴位埋线治疗单纯性肥胖的临床随机对照试验文献,用Revman 5.2软件对结果进行Meta分析。共19篇文献,1 658例患者纳入本次研究。19篇文献均以有效率作为主要结局指标,对同质性较强的研究进行Meta分析,显示穴位埋线组与其他疗法组相比较,合并后OR=2.45,95%CI[1.81,3.32]。总体效应检验,Z=5.81,P<0.01,两者在治疗单纯性肥胖方面,疗效差异具有统计学意义。亚组分析:疗程≥3个月时,穴位埋线相对于其他疗法合并后,OR=2.61,95%CI[1.53,4.46],效应检验,Z=3.51,P<0.01,两者在治疗单纯性肥胖方面,有效率差异有统计学意义;疗程<3个月时,穴位埋线相对于其他疗法合并后,OR=2.38,95%CI[1.65,3.44],效应检验,Z=4.64,P<0.01,提示两者在治疗单纯性肥胖方面,有效率差异具有统计学意义。穴位埋线组与电针组对比,OR=1.79,95%CI[1.08,2.95],P=0.02;穴位埋线组与针刺组对比,OR=1.89,95%CI[1.16,3.09],P=0.01。提示穴位埋线与电针或针刺相比较,疗效有显著差异。说明穴位埋线治疗单纯性肥胖临床疗效优于其他疗法。The clinical therapeutic effect of acupoint catgut-embedding for simple obesity was systemically analyzed to provide reference and assistance for its clinical treatment and research. By searching in the CBM, CNKI, VIP, Wanfang, Puhmed, Springer and Medline databases, clinical randomized controlled trials （RCT） of acupoint catgut-embedding for simple obesity published from Jan, 2009 to July, 2013 were collected while Revman 5.2 software was applied to perform the Meta-analysis. Totally 19 articles were acquired with 1 658 cases involved. The effective rate was selected as primary outcome measure in 19 articles. The Meta-analysis was performed among homogeneous researches. The results indicated that compared with other therapies, pooled OR of acupoint catgut-embedding was 2.45 with 95% CI [1.81, 3.32]; in the test for overall effect, Z=5.81, implying the efficacy difference of two therapies was significant in the treatment of simple obesity （P〈0. 01）. In subgroups analysis, in the event of treatment session with more than 3 months, compared with other therapies, pooled OR of aeupoint catgut-embedding was 2. 61 with 95% CI [1.53, 4.46]; in test for overall effect, Z=3.51, implying the efficacy difference of two therapies was significant in the treatment of simple obesity （P〈0. 01）; in the event of treatment session with less than 3 months, compared with other therapies, pooled OR of acupoint catgut-embedding was 2.38 with 95% CI[1.65, 3.44] ; in test for overall effect, Z = 4.46, implying in the treatment of simple obesity the efficacy difference of two therapies was significant （P〈0. 01）. Compared with electroacupuncture, OR of acupoint catgut-embedding was 1.79, 95% CI [1.08, 2. 95] （P=0. 02）. Compared with acupuncture, OR of acupoint catgut-embedding was 1.89, 95% CI[1.16, 3.09] （P= 0.01）, which explained that compared with electroacupuncture and acupuncture, the efficacy of acupoint catgut-embedding was significantly different. In a word, the clinical efficacy of acupoint catgut-emb

关 键 词：单纯性肥胖 穴位埋线 META分析 

分 类 号：R224[医药卫生—中医基础理论]