2株乳酸菌对小鼠血清中IgG及IgA含量影响的研究  

Study on the Influence of 2 Strains of Lactobacilluson the Content of IgG and IgA in Blood Serum of Mice

作　　者：吕天星[1] 于晨龙[1] 陈光明[1] 杨晓宇[1] 苏日娜[1] 张七斤[1] 

机构地区：[1]内蒙古农业大学兽医学院农业部动物临床诊疗技术重点实验室,内蒙古呼和浩特010018

出　　处：《中国畜牧兽医》2014年第6期117-120,共4页China Animal Husbandry & Veterinary Medicine

基　　金：国家自然基金(31160508)

摘　　要：本试验以2株乳酸菌(LJ2和LZ1)按不同剂量分别对小鼠连续灌服30d,在10、20、30d检测各组小鼠血清中IgG和IgA的含量。结果表明,灌服不同剂量的LJ2和LZ1菌液均能提高小鼠血清中IgG、IgA含量,且随灌服时间的不断增加,低、中剂量组有超过高剂量组的趋势。整体上看,灌服LZ1菌液对提高血清中IgG、IgA含量的效果优于LJ2菌液,其中LZ1的低剂量组对于提高机体免疫力效果最好,中、高剂量组次之,最后是低剂量LJ2。In this test, the LJ2 and LZ1 Lactobacillus strains had been given to mice with different doses for 30 days continuously by the way of intragastric administration. Then we detected the content of IgG and IgA in blood serum of mice at 10,20 and 30 days. The results showed that compared with the control group,all the different groups with different doses of LJ2 or LZ1 could significantly increase the content of IgG and IgA in blood serum of mice, and the low-dose group and middle-dose group tended to exceed the high-dose group with time passing. All in all,for the increase of the content of IgG and IgA in blood serum of mice,the LZ1 strain had a better effect than the LJ2 strain. The sequence according to the effect was listed from the best to usual as following：The LZ1 low-dose group had the best effect,then came to the LZ1 middle-dose group and high-dose group,the last was the LJ2 low-dose group.

关 键 词：乳酸菌液 小鼠 IGG IGA 

分 类 号：S852.43[农业科学—基础兽医学]