巨痣侵及脂肪和肌肉层并高度怀疑并发神经皮肤黑变病：病例报道及文献复习  

Giant congenital melanocytic nevus extended into the fat and muscle with potential neurocutaneous me- ianosis： case report and literature review

作　　者：魏蜀一[1] 周传德[1] 李强[1] 李森恺[1] 李峰永[1] 周宇[1] 丁健[1] 曹玉娇[1] 张思娅[1] 

机构地区：[1]中国医学科学院北京协和医学院整形外科医院整形十科,北京100144

出　　处：《中国美容整形外科杂志》2014年第6期356-359,共4页Chinese Journal of Aesthetic and Plastic Surgery

摘　　要：目的探讨巨痣的疾病特点，提高对巨痣的临床诊治水平。方法对1例罕见巨痣病例进行报道，并结合文献报道的资料进行分析总结。结果本例患者19岁，自出生即被发现项背部巨痣，在我院行病变组织切除植皮术，术中发现痣细胞侵及脂肪和肌肉层。随访7年，高度怀疑并发神经皮肤黑变病。结论结合本病例及文献分析，整形外科医师应认识到巨痣的痣细胞可能侵犯较深（甚至达脂肪、肌肉层），且可能并发神经皮肤黑变病。因此，手术前应全面系统考虑患者的病史、可能的并发症及首选的治疗手段，必要时应与皮肤科及神经科多学科合作共同完成治疗，以防延误病情，减少并发症发生的风险。Objective To review and summarize the clinical features and treatment of giant congenital melanocytic nevus. Methods To study the clinical manifestation, treatment and outcome of a 19-year-old girl with giant congenital melanocytic nevus and review recent literature. Results The 19-year-old patient with giant congenital melanocytic nevus was performed the resection, which invaded the fat and muscle layer, the wound was treated with grafting. The lesion was found to become the potential NCM during the 7 years following up. Conclu- sion Plastic surgeons should be aware that the melanocytes may invade deeply （ fat and muscle layers） and may have the complication of NCM. Plastic surgeons should cooperate with neurologists and dermatologist for the treat- ment of giant congenital melanoeytic nevus in some conditions to decrease the complications.

关 键 词：巨痣 并发症 神经皮肤黑变病 

分 类 号：R741.02[医药卫生—神经病学与精神病学]