利用磁敏感加权成像技术检测脑内微出血  

Micro magnetic sensitive weighted imaging for intracerebral hemorrhage

作　　者：周忠洁[1] 赵晓君[1] 陈梅魁[1] 蔡志胜[1] 

机构地区：[1]温州医科大学附属第二医院放射科,325027

出　　处：《中华医学杂志》2014年第21期1661-1663,共3页National Medical Journal of China

摘　　要：目的利用磁敏感加权成像（SWI）检测脑内微出血，并探讨脑出血、脑内微出血与脑血管病危险因素之间的关系。方法回顾性分析从2012年8月至2013年6月于温州医科大学附属第二医院进行了SWI检查的患者共70例，其中男42例、女28例，年龄30～88（68±14）岁。总结患者的性别、年龄、高血压、糖尿病、高血脂情况。由一名具有10年以上MRI经验的主任医师对常规MRI影像及SWI图像进行分析，记录脑梗死、陈旧出血的发生情况及脑微出血的个数。然后运用SPSS13．0对资料进行统计分析，以脑出血为因变量，以脑内微出血、脑血管的高危因素为自变量做二元逻辑回归分析；以脑内微出血的数量为因变量，以性别、年龄、脑出血、脑血管的高危因素为自变量做线性回归分析。按P〈0．05为差异有统计学意义。结果脑内微出血的个数为0—65个；44例发生过梗死，7例发生过陈旧出血；经二元逻辑回归分析发现脑内出血与高脂血症有相关性（P=0．017）；经线性回归分析发现脑微出血与脑出血有相关性（P=0．023）。结论SWI评价脑内微出血有助于评估脑血管病患者脑出血发生的可能性，为临床治疗及采取相应预防措施提供依据。Objective To detect cerebral microbleeds by susceptibility weighted imaging and explore the relationship between intracerebral hemorrhage, cerebral mierobleeds and risk factors of cerebral vascular disease. Methods A retrospective analysis was conducted for 70 patients from August 2012 to June 2013 undergoing susceptibility weighted imaging （SWI）. The average age was （68 ± 14 ） years. Their demographic and clinical profiles were recorded. Conventional magnetic resonance imaging （MRI） and SWI images were performed and images analyzed by an experienced radiologist. The occurrence of infarction, hemorrhage and number of microbleeds were recorded. Then regression analysis with SPSS 13.0 was used to define the relationship between the existence of infarction, hemorrhage and the number of microbleeds. Results There were 0 - 65 microbleeds in brains on SWI. There were infarction （ n = 44 ） and chronic intracranial hemorrhage （ n = 7 ）. The binary Logistic regression analysis showed that intracranial hemorrhage was associated with hyperlipidemia （P = 0. 01 ）. Linear regression analysis showed that the number of microbleeds was related with intraeranial hemorrhage （ P = 0. 02 ）. Conclusion Evaluation of microbleeds in brain by SWI may help to assess the possibility of intracranial hemorrhage so as to provides rationales for clinical therapeutics.

关 键 词：磁共振成像 脑出血 脑血管障碍 

分 类 号：R743.34[医药卫生—神经病学与精神病学]