改良电痉挛治疗与686项目结合治疗精神分裂症阳性症状  

Integrated Therapy with Modified Electric Convulsive Therapy and 686 Project for Positive Symptoms of Schizophrenia

作　　者：强瑞香 高海江[1] 刘炳书 高海英[1] 张淑艳[1] 王晓荣[2] 王晓华[1] 邹永江 

机构地区：[1]秦皇岛市九龙山医院,中国066601 [2]秦皇岛市第三医院

出　　处：《中国健康心理学杂志》2014年第5期658-660,共3页China Journal of Health Psychology

摘　　要：目的探讨改良电痉挛治疗(MECT)与686项目结合治疗精神分裂症阳性症状的临床疗效。方法将299例686项目精神分裂症患者随机分为两组,分别给予MECT与利培酮治疗8周。采用简明精神病评定量表(BPRS)、阳性症状量表(SAPS)、不良反应量表(TESS)评定疗效及不良反应。结果实验组治疗总有效率为91.33%,利培酮组为62.41%,两组比较差异有统计学意义(χ2=4.62,P<0.05)。实验组的锥体外系反应、窦速和停经泌乳等不良反应低于对照组(χ2=9.50,6.91,4.95;P<0.05)。结论 MECT与686项目结合治疗精神分裂症阳性症状安全有效。Objective To explore the clinical effect of therapy of MECT and 686 project for schizophrenia. Methods A total of 299 schizophrenia patients of 686 project randomly divided into two groups were given a treatment of MECT and Risperidone for 8 weeks. The brief psychiatric rating scale（BPRS） , the positive syndrome scale（SAPS） and the Treatment Emergent Sympteol Scale（TESS） were used to evaluate the efficacy and adverse reaction. Results The total effectiveness of the study group was 91.33% ,while the control group 62.41%. The comparison difference of the two groups was statistically significant （ X2 = 4.62, P 〈 0.05 ）. Team of extrapyramidal reactions, sinus tachycardia and amenorrhea lactation syndrome adverse reaction were lower than the control group （X2 = 9.50,6.91,4.95 ;P 〈 0.05 ）. Conclusion The combined therapy of MECT and 686 project is safe and effective for positive symptoms of schizophrenia.

关 键 词：改良电痉挛治疗 686项目 精神分裂症 阳性症状 

分 类 号：R749.054[医药卫生—神经病学与精神病学]