瘤体实质 ADC 值及 EDC 值在颅内淋巴瘤与Ⅲ-Ⅳ级星形细胞瘤鉴别中的应用  

The Application of ADC and EDC Value in Differentiation Between Intracranial lymphoma and Grade Ⅲ～ Ⅳ Astrocytoma

作　　者：陈兵[1] 李辉[2] 李春花[2] 石洋洋 

机构地区：[1]宁夏医科大学总医院放射科,银川750004 [2]宁夏医科大学,银川750004

出　　处：《临床放射学杂志》2014年第6期818-821,共4页Journal of Clinical Radiology

基　　金：2009年度宁夏自然科学基金项目(编号:NZ09220)

摘　　要：目的探讨瘤体实质表观扩散系数（ADC）值、指数扩散系数（EDC）值在颅内淋巴瘤与Ⅲ～Ⅳ级星形细胞瘤鉴别中的价值。方法搜集经术后病理确诊的19例颅内淋巴瘤和45例Ⅲ～Ⅳ级星形细胞瘤的影像学资料，包括常规MRI平扫、增强扫描和扩散加权成像，测量瘤体实质区、瘤体对侧正常脑白质区的ADC值及EDC值。然后对两组肿瘤的瘤体实质ADC值、EDC值、rADC值、rEDC值分别进行两样本t检验。结果颅内淋巴瘤的瘤体实质ADC值低于Ⅲ～Ⅳ级星形细胞瘤（t=-7．416，P=0．004），rADC值低于Ⅲ-Ⅳ级星形细胞瘤（t=-7．181，P=0．003），EDC值高于Ⅲ～Ⅳ级星形细胞瘤（t=8．101，P：0．030），rEDC值高于Ⅲ～Ⅳ级星形细胞瘤（t=8．055，P=0．002）。结论颅内淋巴瘤与Ⅲ一Ⅳ级星形细胞瘤瘤体实质ADC值、EDC值、rADC值、rEDC值结合DWI图像及常规MRI平扫＋增强有助于颅内淋巴瘤与Ⅲ～Ⅳ级星形细胞瘤的鉴别诊断，瘤体实质ADC值及EDC值的测量对两种肿瘤的鉴别有很大的应用价值。Objective To explore the value of ADC and EDC in differentiating intracranial lymphoma and grade Ⅲ～Ⅳ Astrocytoma. Methods Imaging material, including conventional MRI, enhanced MRI and DWI of 19 cases of intracranial lymphoma and 45 cases of grade Ⅲ～Ⅳ Astrocytoma were collected. The ADC value and EDC value was measured in the enhanced area of tumor, the contralateral normal - appearing white matter respectively. The ADC values, EDC values, rADC values and rEDC values in intracranial lymphoma were compared with those in grade Ⅲ～Ⅳ astrocytoma u- sing a two tailed t test. Results ADC value in intracranial lymphoma was lower than that in grade Ⅲ～Ⅳ astrocytoma（ t = -7. 181 ,P =0.003） ,rADC value was lower than that in grade Ⅲ～Ⅳ astrocytoma（t = -7. 181 ,P =0.003） ,EDC val- ue was higher than that in grade Ⅲ～Ⅳ astrocytoma（ t = 8. 101 ,P = 0.030） , rEDC value was higher than that in grade Ⅲ～Ⅳ astrocytoma（ t = 8. 055,P = 0.002）. Conclusion ADC value, EDC value, rADC value and rEDC value of tumor have statistical significant difference between intraeranial lymphoma and grade Ⅲ～Ⅳ astrocytoma. It is valuable of ADC and EDC value in differentiating intracranial lymphoma and grade Ⅲ～Ⅳ astrocytoma.

关 键 词：表观扩散系数 指数表观扩散系数 淋巴瘤 颅内 Ⅲ~Ⅳ级星形细胞瘤 

分 类 号：R739.4[医药卫生—肿瘤]