儿童急性淋巴细胞白血病治疗效果及预后  

The Treatment Effect and Prognosis of Children with Acute Lymphoblastic Leukemia

作　　者：吴小建[1] 

机构地区：[1]九江学院附属医院,江西九江332000

出　　处：《中国医学创新》2014年第16期66-68,共3页Medical Innovation of China

摘　　要：目的:探讨并研究儿童急性淋巴细胞白血病治疗效果及预后。方法:选取2011年12月-2013年12月本院收治的儿童急性淋巴细胞白血病患者120例,按随机数字表法分为两组各60例,对照组采用甲氨蝶呤进行治疗,试验组采用甲氨蝶呤结合四氢叶酸钙联合进行治疗。比较两组的临床效果。结果:试验组治疗效果较好,总缓解率高于对照组,不良反应明显低于对照组,差异均有统计学意义(P<0.05)。结论:采用甲氨蝶呤结合四氢叶酸钙联合治疗儿童急性淋巴细胞白血病,能够有效地提高急性淋巴细胞白血病的治疗疗效,降低药物治疗的风险,保证患者在治疗中的安全;且患者在治疗中出现的不良反应较少,患者以及患者家属能够接受,值得临床推广。Objective：To research and study the treatment effect and prognosis of.Method：120 children with acute lymphoblastic leukemia,who had treated in our hospital from December 2011 to December 2013 were selected, and were randomly divided into two groups,each group had 60 cases. The control group was treated with Methotrexate and the experimental group was treated with Methotrexate combined with Four hydrogen folic acid calcium. The clinical effect of the two groups were compared.Result：The experimental group had a effective treatment,and the total curative effect was significantly higher than the control group,the adverse reaction was significantly lower than the control group,the differences were statistically significant（P〈0.05）.Conclusion：Using folinic acid with methotrexate to treat the children with acute lymphoblastic leukemia has a effective treatment,the methods can effectively improve the treatment effect of acute lymphoblastic leukemia,reduce the risk of drug treatment and adverse reactions,and be able to ensure the safety of the patients in the treatment,which patients and his families could accept. therefore,worthy of clinical promotion.

关 键 词：急性淋巴细胞白血病 甲氨蝶呤 临床效果 

分 类 号：R733.72[医药卫生—肿瘤]