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作 者:杨雪琴[1] 刘顺达[1] 高娟[1] 王喜全[1] 韩海平[1]
机构地区:[1]宁夏回族自治区人民医院神经内科,宁夏银川750001
出 处:《现代生物医学进展》2014年第21期4130-4133,共4页Progress in Modern Biomedicine
基 金:宁夏自治区卫生厅重点科研计划课题资助项目(2012079)
摘 要:目的:研究蒙特利尔认知评估量表(MoCA)诊断临界值在宁夏回族自治区患有血管性认知功能障碍(VCI)中的应用价值。方法:对宁夏回族自治区人民医院神经内科住院治疗的126例脑血管功能性认知缺陷患者分为非痴呆性血管认知功能障碍(VCIND)组53例、认知功能正常(NCI)组47例和血管性痴呆(VaD)组26例,分别予以简易精神状态量表(MMSE)和MoCA进行认知能力检测,分析比较三组患者的诊断效果。结果:将认知功能障碍MoCA临界值<26分定义认知功能障碍时,VCIND组MoCA评分结果显示敏感度86.8%、准确度94.3%;VaD组敏感度100.0%、准确度88.5%与MMSE比较均有统计学意义(P<0.05)。结论:采用MoCA在VCI筛查评估中的诊断效果极佳,具有良好的敏感性、特异度和信度,临床推荐应用。Objective: To analyze the application value of the Montreal cognitive assessment (MoCA) in diagnosis of the vascular cognitive impairment (VCI) in Ningxia Hui autonomous region. Methods: 126 patients with cerebro-vascular functional cognitive defects who were treated at the neurology department of People's Hospital of Ningxia Hui autonomous region were divided into non dementia (VCIND) vascular cognitive dysfunction group (53 cases), cognitive functioning (NC1) group (47 cases) and vascular dementia (VaD) group (26 cases). They were tested with simple mental state scale (MMSE) and MoCA cognitive ability assessment. The diagnosis effects were analyzed and compared between the three groups. Results: The cognitive dysfunction MoCA threshold 〈26 points defined as cognitive dysfunction, the MoCA score results of VCIND group showed a sensitivity of 86.8%, and an accuracy of 94.3%; and sensitivity of 100.0% and accuracy of 88.5% for VaD group. Compared with MMSE, there was statistical significance (P〈0.05). Conclusion: MoCA had an excellent effect in VCI screening evaluation, with good reliability, sensitivity, specific degrees and clinical application.
分 类 号:R741.02[医药卫生—神经病学与精神病学]
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