CD34^+细胞在原发性骨髓纤维化症和原发性血小板增多症骨髓组织中的表达  

Expression and significance of CD34^+ in PMF and ET

作　　者：田林涛[1] 王宗超[1] 梁漫[1] 王新梅[1] 田亚宁[1] 王越月[1] 李宏[1] 何春玲[1] 董昌虎[2] 

机构地区：[1]陕西中医学院,咸阳712000 [2]陕西中医学院第二附属医院

出　　处：《陕西医学杂志》2014年第6期648-649,666,共3页Shaanxi Medical Journal

基　　金：陕西省自然科学基金项目(2011JM4007);咸阳市科技计划项目(2012k16-03)

摘　　要：目的:探讨CD34+细胞在原发性骨髓纤维化症及原发性血小板增多症骨髓组织中的表达及临床意义。方法:应用免疫组织化学染色法,检测原发性骨髓纤维化症和原发性血小板增多症实验组及对照组骨髓组织中CD34+细胞表达情况。结果:CD34+细胞在实验组骨髓组织中表达高于对照组,差异有统计学意义(P<0.05);CD34+细胞在原发性骨髓纤维化症及原发性血小板增多症骨髓组织中表达的差异无统计学意义(P>0.05)。结论:CD34+细胞在原发性骨髓纤维化症和原发性血小板增多症的发生中有一定关系,CD34+细胞与两者之间的转化无必然联系。Objective：To investigate the expression and clinical significance of CD34＋in PMF and ET.Methods：Using immunohistochemical staining to test the expression and clinical significance of CD34in PMF and ET.Results：The CD34＋cells were highly expressed in PMF and ET than contrast,the difference was statistically significant（P〈0.05）;The CD34＋cells were expressed in PMF and ET＇s bone marrow tissue,there was no statistically significant difference（P〉0.05）.Conclusion：The CD34＋cells may be not associated with MPN occurrence,development relationship,The transformation between the not necessarily linked.

关 键 词：原发性骨髓纤维化 血小板增多 抗原 CD34 骨髓细胞 

分 类 号：R733[医药卫生—肿瘤]