维生素D及其与牙周炎的关系  

Vitamin D and its relationship with periodontitis

作　　者：仝春实 邹永巍[1] 王雷[1] 宫俊霞 李文然[1] 刘长欢[1] 卢建忠[1] 

机构地区：[1]吉林大学口腔医院口腔颌面外科 [2]中日联谊医院口腔科,长春130021

出　　处：《国际口腔医学杂志》2014年第4期474-477,共4页International Journal of Stomatology

摘　　要：维生素D是一种脂溶性维生素,既可内源性合成,也可通过日常饮食或者膳食获得。维生素D缺乏,在儿童会引起佝偻病,在成人则会导致骨质疏松。维生素D缺乏会增加罹患牙周炎的风险,加重牙周炎的严重程度,增加失牙率;反之,血清维生素D水平充足则更易获得健康的牙周组织。在牙周疾病治疗时,适当的血清维生素D水平,不仅可以降低失牙率和牙周炎的发病率,还可促进牙周组织愈合。补充维生素D对维护牙周健康,尤其是对探诊出血、牙龈指数和探诊深度的改善有明显的效果,可增加颌骨骨密度,抑制牙槽骨吸收。维生素D对牙周炎发病及其严重程度的影响,可能缘于其对骨钙代谢的调节作用以及对牙周致病菌和参与牙周破坏的炎症递质的抑制作用。本文就维生素D及其与牙周炎的关系等研究进展作一综述。Vitamin D is a fat-soluble Vitamin that can be obtained from endogenous synthesis, dietary sources, and dietary supplements. Rickets and osteoporosis are well-known diseases associated with Vitamin D deficiency. Vitamin D deficiency is also associated with periodontitis. Vitamin D deficiency can increase the rate of periodontitis, severity of periodontitis, and rate of tooth loss. Individuals with adequate serum Vitamin D levels are more likely to maintain periodontal health. Appropriate serum Vitamin D levels can reduce the incidence of tooth loss and periodontitis, as well as promote wound healing. Vitamin D supplementation is important in maintaining periodontal health, especially for bleeding on probing, gingival index, and probing depth. Vitamin D can increase the alveolar bone density and inhibit alveolar bone loss. Vitamin D may be benefi cial for oral health because of its direct effect on bone metabolism, and its ability to function as an anti-infl ammatory agent and stimulate the production of anti-microbial peptides. This article reviews the research progress on Vitamin D, and the relationship between Vitamin D and periodontitis is analyzed.

关 键 词：维生素D 牙周炎 口腔健康 

分 类 号：R781.4[医药卫生—口腔医学]