卒中后失语患者非语言性认知功能特点的临床研究  

Clinical study of the characteristics of the non-language-based cognitive function in patients with aphasia after stroke

作　　者：王琪[1] 刘晓加[1] 吴积宝[1] 李园[1] 

机构地区：[1]南方医科大学南方医院神经内科,广州510515

出　　处：《中华行为医学与脑科学杂志》2014年第6期487-489,共3页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：南方医院院长基金项目（2012A002）

摘　　要：目的 探讨卒中后失语患者的非语言性认知功能特点.方法 纳入30例卒中后失语患者和30例卒中后非失语患者,对失语组采用汉语失语检查量表（Aphasia Battery of Chinese,ABC）进行失语评估,并用非语言性的认知功能评定量表（The Non-language-based Cognitive assessment,NLCA）评估卒中后失语患者和非失语患者的认知功能.用卒中后失语患者抑郁问卷（医院版）（Stroke Aphasic Depression Questionnaire Hospital Version,SADQ-H）评估卒中后失语患者的抑郁情绪,比较失语患者的抑郁情绪与认知功能损伤之间的关系.结果 失语组的NLCA总分（50.01±14.01）分显著低于非失语组（66.13±5.95）分,差异具有统计学意义（P＜0.05）;失语组的NLCA总分及其各亚项分值均与ABC总分及其各亚项分值具有相关性（P＜0.01,P＜0.05）;失语组SADQ-H总分（21.83±7.37）分显著高于非失语组SADQ-H总分（16.13±5.84）分,差异具有统计学意义（P＜0.01）;失语组SADQ-H评分与NLCA总分呈显著负性相关（r=-0.468,P＜0.05）.结论 卒中后失语患者存在非语言性认知功能障碍,并且失语患者抑郁情绪的严重程度对认知功能的损伤有影响.Objective To analyze the characteristics of the non-language-based cognitive function in patients with aphasia after stroke.Methods Thirty patients of the first infarction with aphasia and thirty stroke patients without aphasia were recruited.The aphasia deficits in patients were evaluated using the Aphasia Battery of Chinese（ABC）.The non-language-based cognitive assessment scale （NLCA） was applied to analyze the cognitive function in the two groups.The stroke aphasic depression questionnaire hospital version （SADQ-H）was applied to analyze the depression in the two groups.Results The score in NLCA of the aphasia group was significantly lower than that of control group（（50.01± 14.01）vs（66.13±5.95）,P〈0.01）.There was high correlation between the total and sub-scores of NLCA and ABC in both groups（P〈0.01,P〈0.05）.The score in SADQ-H of the aphasia group was significantly higher than that of control group（（21.83±7.37）vs（16.13±5.84）,P〈0.01）.The total score for the aphasia patients shown by the SADQ-H was negatively related with the total score of the NLCA（r=-0.468,P〈0.05）.Conclusion There is non-language-based cognitive dysfunction in patients with aphasia after stroke,and the severity of depression affects cognitive function.

关 键 词：卒中 失语 认知功能障碍 非语言性认知功能评估量表 

分 类 号：R743.3[医药卫生—神经病学与精神病学]