社交焦虑障碍患者及其一级亲属持续性操作测验的研究  

Study on continuous performance test in the patients with social anxiety disorder and their first degree relatives

作　　者：杜启峰 张校明[5] 于妍 李功迎[5] 张建龙 胡静 张文蔚 

机构地区：[1]中山市第三人民医院情感障碍科,中山528451 [2]中山市第三人民医院临床心理科,中山528451 [3]中山市第三人民医院科教信息科,中山528451 [4]中山市第三人民医院司法鉴定科,中山528451 [5]济宁市精神病防治院精神科

出　　处：《中华行为医学与脑科学杂志》2014年第6期504-506,共3页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：山东省医药卫生科技发展计划项目（2011WSA08018）

摘　　要：目的 探索社交焦虑障碍（SAD）患者及其一级亲属持续性注意功能的特征.方法 收集58例SAD患者及68名一级亲属和60例正常对照者分别进行持续性操作测验（CPT）.结果 在简单操作（RT）中,SAD患者组各项指标[舍弃数（5.2±6.9）个、漏答数（6.7±13.6）个、反应时间（421.0±112.0） ms及变异系数（47.3±38.1）％]均高于一级亲属组[舍弃数（2.9±3.3）个、漏答数（1.5±2.1）个、反应时间（342.0±47.0）ms及变异系数（28.9±10.1）％]及正常对照组[舍弃数（2.8±2.9）个、漏答数（1.3±0.7）个、反应时间（329.0±53.0）ms及变异系数（27.8±9.7）％],差异均有统计学意义（P＜0.01）,而后两组差异无统计学意义（P＞0.05）.而在复杂操作（XT）中,SAD患者一级亲属组CPT指标介于两者之间,差异有统计学意义（P＜0.05）.结论 SAD一级亲属在简单操作中未表现出注意功能障碍,而在复杂操作中SAD患者及其一级亲属都存在一定程度注意功能缺陷.Objective To explore the features of sustained attention in the patients with social anxiety disorder and their first degree relatives.Methods 60 cases of normal controls,58 cases of patients with social anxiety disorder and 68 cases of their first degree relatives were performed with continuous performance test.Results In reaction time task（a simple performance）,all of CPT parameters in patient group （number of cancel （5.2±6.9）,number of omission（6.7± 13.6）,reaction time（421.0± 112.0） ms,variance coefficient（47.3±38.1） %）were higher than those in the first degree relatives group（number of cancel （2.9± 3.3）,number of omission （1.5±2.1）,reaction time （342.0±47.0） ms,variance coefficient（28.9± 10.1） %） and controlled group （number of cancel （2.8 ± 2.9）,number of omission （1.3 ± 0.7）,reaction time （329.0 ± 53.0） ms,variance coefficient （27.8± 9.7） %）,the differences were significant（P〈0.01）,while all of CPT parameters in the first degree relatives were similar to those in controlled group（P〉0.05）.In X task （a complex performance）,the results of CPT in the first degree relatives were between the patients and the normal controls,and the differences were statistically significant（P〈0.05）.Conclusion The anxiety disorder patients showed no sustained attention impairment in simple performance while in a complex performance there were some defects of sustained attention functions in the patients with social anxiety disorder and their first degree relatives.

关 键 词：社交焦虑障碍 一级亲属 持续性注意功能 

分 类 号：R749.7[医药卫生—神经病学与精神病学]