成人松果体实质细胞肿瘤的治疗  

Treatment for pineal parenchymal tumors in adult patients

作　　者：张斌[1] 林松[1] 于洮[1] 

机构地区：[1]首都医科大学附属北京天坛医院神经外科,100050

出　　处：《中华神经外科杂志》2014年第6期549-551,共3页Chinese Journal of Neurosurgery

摘　　要：目的探讨成人松果体实质肿瘤的手术疗效。方法回顾性分析北京天坛医院神经外科2007年1月至2013年10月收治了39例成人（≥18岁）松果体实质细胞肿瘤的临床资料并进行随访。结果肿瘤全切除19例，次全切除12例，部分切除6例，仅行肿瘤活检2例，无手术死亡病例。术后病理结果：松果体细胞瘤14例，中分化松果体实质肿瘤15例，松果体母细胞瘤10例。随访到的32例患者中，5例患者因肿瘤复发而死亡，中分化和松果体母细胞瘤中位生存期分别为34．5个月和29．8个月。结论松果体细胞瘤手术治疗效果良好，中分化松果体实质肿瘤和松果体母细胞瘤治疗应首选手术，放化疗的效果尚待确定。Objective To study the clinical characteristics, surgical treatment and outcome of pineal parenchymal tumors（PPF） in adult patients. Methods The adult patients （ ≥ 18 years old） with PPT diagnosed between 2（D7 and 2013 were retrospectively studied and their surgical results were followed - up. Results 37 PPT tumors were surgically removed,including 19 total removal,12 subtotal removal and 6 partial removal. The biopsy was made in 2 patients. The pathological type of 14 cases was pineocytoma, 15 pineal parenchymal tumors of intermediate differentiation, and 10 pinealoblastoma. In 32 patients of follow -up, there were 5 patients died because of tumor recurrence. The median overall survival was 34. 5 months for intermediate differentiation and 29. 8 months for pinealoblastoma. Conclusions Pineeeytomas＇ patients have good survival prognosis after surgical treatment. Microsurgery is the most effective therapy for pineal parenchymal tumor of intermediate differentiation and pineoblastoma. The role of adjuvant radiotherapy and chemotherapy remains to be defined.

关 键 词：松果体肿瘤 治疗 手术 成人 

分 类 号：R739.4[医药卫生—肿瘤]