超声引导下聚桂醇硬化治疗单纯性肝囊肿疗效及安全性分析  

Ultrasound- guided lauromacrogol sclerotherapy of simple liver cyst: analysis of its efficacy and safety

作　　者：包作伟[1] 张伟民[1] 邵珍[1] 符文育[1] 

机构地区：[1]常州市第三人民医院超声科,213001

出　　处：《介入放射学杂志》2014年第6期520-522,共3页Journal of Interventional Radiology

摘　　要：目的对比分析聚桂醇注射液与无水乙醇治疗单纯性肝囊肿的疗效与安全性。方法将单纯性肝囊肿患者分为聚桂醇组(86例,研究组)与无水乙醇组(80例,对照组),实施在超声引导下穿刺抽液硬化治疗,对比观察两组患者的疗效及不良反应。结果两组均未出现出血、感染等并发症。治疗过程中对照组45例(56.3%)患者出现不同程度疼痛,23例(28.8%)出现醉酒样症状;研究组无明显不适。治疗后1周,对照组20例(25.0%)患者仍有右上腹胀痛,研究组仅9例(10.5%),差异有统计学意义(χ2=6.073,P<0.05);随访6个月,聚桂醇组治愈率95.7%,无水乙醇组93.5%,两组间差异无统计学意义(P>0.05)。结论聚桂醇注射液在肝囊肿硬化治疗中安全有效,值得临床推广应用。Objective To compare the efficacy and safety of lauromacrogol injection sclerotherapy with ethanol injection sclerotherapy in treating simple liver cysts. Methods A total of 166 patients with simple liver cyst were randomly divided into the lauromacrogol group （study group, n=86） and the absolute alcohol group （control group, n=80）. Under ultrasonographic guidance, puncture aspiration of liver cyst was carried out in all patients, which was followed by injection of lauromacrogol for patients in the study group or injection of ethanol for patients in the control group. The therapeutic effect and the side-effect were evaluated. The results were compared between the two groups. Results No serious complications such as bleeding or infection occurred in both groups. During the therapeutic course , 45 patients （56.3%） in the control group felt pain to some degree and 23 patients （28.8%） developed drunk-like symptoms, while no patient in the study group felt any obvious discomfort. One week after sclerotherapy , 20 patients （25%） in the control group complained of distending pain on the right upper abdomen, while only 9 patients （10.5%） in the study group complained of pain, and the difference was statistically significant （χ2= 6.073, P 0.05）. Conclusion For the treatment of liver cysts, lauromacrogol injection is safe and effective. Therefore, this technique should be recommended in clinical practice.

关 键 词：聚桂醇 无水乙醇 肝囊肿 硬化治疗 

分 类 号：R735.7[医药卫生—肿瘤]