男性与女性胰腺实性假乳头状瘤的临床表现和多层螺旋计算机断层扫描特征比较  

Comparison of clinical manifestation and multi-slice computed tomography characteristics in pancreas solid pseudopapillary tumor between male and female patients

作　　者：胡曙东[1] 谌业荣[1] 王亚非[1] 宋琦[2] 林晓珠[2] 王忠敏[2] 陈克敏[2] 

机构地区：[1]江苏大学附属人民医院放射科,江苏省镇江市212002 [2]上海交通大学医学院附属瑞金医院放射科

出　　处：《中华消化杂志》2014年第6期396-399,共4页Chinese Journal of Digestion

基　　金：国家自然科学基金（81071281、81271682）;上海市科学技术委员会生物医药重点项目（10JC1410900、10411953000、11JC1407400）

摘　　要：目的 回顾性分析男性胰腺实性假乳头状瘤（SPT）的临床和多层螺旋CT （MSCT）表现,并和女性胰腺SPT患者进行对照研究.方法 收集2000年11月至2012年10月行MSCT检查且病理最终确诊为胰腺SPT的18例男性和94例女性患者,共112例.分析男性与女性胰腺SPT的临床特征和MSCT表现,包括病变部位、大小、形态、包膜、钙化、内部组成、密度、CT强化模式.采用秩和检验和卡方检验对上述结果进行统计学处理.结果 男性患者中位年龄为39.0（15.0,67.0）岁,明显大于女性患者的27.5（11.0,63.0）岁,差异有统计学意义（U=2.865,P=0.005）,男、女胰腺SPT患者的临床表现、肿瘤部位和良恶性构成比之间差异均无统计学意义（P均＞0.05）;MSCT表现中,男性胰腺SPT患者中肿瘤最大径明显小于女性患者[5.1（1.0,11.6）cm比7.9（2.5,18.7） cm,U=3.161,P=0.002];实性肿瘤较女性多见[9/18比5.3％（5/94）],差异均有统计学意义（x2=30.606,P＜0.01）.结论 男性胰腺SPT影像学特征不同于女性患者.对于男性胰腺病变,MDCT表现为实性成分较多,病灶较小,具有典型SPT的强化模式,应考虑SPT的可能.Objective To retrospectively analyze imaging features of multi-slica computed tomography （MSCT） and clinical characteristics of male patients with pancreas solid pseudopapillary tumor （SPT） and compare with that of female patients.Methods From November 2000 to October 2012,clinical data of 18 male patients and 94 female patients underwent MSCT examination and pathological diagnosed as SPT were retrospectively analyzed.Clinical characteristics and imaging features of MSCT of male and female patients with SPT were analyzed,which included lesion location,size,shape,encapsulation,calcification,internal composition,density and enhancement pattern of tumors.Rank sum test or x2 test was performed for statistical analysis.Results The median age of male patients with SPT was significantly older than that of female patients （39.0 （15.0,67.0） years vs 27.5 （11.0,63.0） years; U=2.865,P =0.005）.There were no significant differences in clinical manifestation,lesion location and composition ratio of benign and malignant tumors between male and female patients with SPT （all P＞0.05）.Imaging of MSCT indicated that the median maximum tumor diameter of male patients with SPT was significantly shorter than that of female patients （5.1 （1.0,11.6） cm vs 7.9 （2.5,18.7） cm; U=3.161,P=0.002）.Solid tumors were more common in male patients compared with female patients （9/18 vs 5.3％ （5/94） ; x2 =30.606,P＜0.01）.Conclusions The imaging features of male patients with SPT are different with those of females.For pancreas lesion in males,if imaging of MSCT shows more solid composition,small lesion and with typical enhancement patterns of SPT,the possibility of SPT should be considered.

关 键 词：胰腺肿瘤 体层摄影术 X线计算机 胰腺实性假乳头状瘤 男性 

分 类 号：R735.9[医药卫生—肿瘤]