MRI自动图像分割技术对多发硬化(MS)病灶容积测量的初步研究  

A Preliminary Study of MS Lesion Volume Measurement by Using MRI Automated Segmentation Technique

作　　者：段阳[1] 杨本强[1] 刘文源[1] 徐猛[1] 李延锋[1] 刘宇[1] 

机构地区：[1]辽宁沈阳军区总医院放射科,辽宁沈阳110015

出　　处：《中国CT和MRI杂志》2014年第3期11-14,共4页Chinese Journal of CT and MRI

摘　　要：目的采用不同序列间组合提高自动图像分割技术对MS病变容积测量。材料和方法以手动分割的病灶容积为金标准,比较不同序列(M,MPRAGE;F,FLAIR;D,DIR;T2,T2WI)间所组合的不同通道(二、三和四通道)的自动分割技术测量MS病灶容积特点。结果二通道(M+T2\M+D\M+F)的敏感性、特异性和精确性分别为:41.8%\33.3%\63.4%、8 2.2%\9 3.9%\9 3.6%和82.1%\99.0%\98.9%;三通道(M+T2+D/M+D+F/M+F+T2)的敏感性、特异性和精确性分别为:40.4%\64.8%\62.5%、8 7.1%/9 9.1%/9 8.6%和86.9%/98.9%/98.5%;四通道(M+T2+D/M+D+F/M+F+T2)的敏感性、特异性和精确性分别为:74.4%、97.0%和96.9%。结论采用四通道图像自动分割技术对MS病灶容积测量较佳。Objective To improve automated technique in MS lesion volume measurement. MaterialsandMethods To compare lesion volume of multiple channels automated segmentation with that of manual segmentation in different sequences of 3D high resolution MRI： （MPRAGE, T2WI, FLAIR and DIR）. Results the sensitivity of M＋T2/M＋T2＋D, M＋D/M＋D＋F, M＋F/M＋F＋T2 and M＋F＋T2＋D were 41.8/40.4%, 33.3/64.8%, 63.4/62.5%, 74.4%; the specificity were 82.2/87.1%, 93.9/99.1%, 99.0/98.6%, 97.0% and the accuracy were 82.1/86.9%, /93.6/98.9%, 98.9/98.5%, 96.9%. Conclusion In automated segmentation, the four channels automated segmentation is the best measurement way in MS lesion volume.

关 键 词：磁共振成像 图像分割 多发硬化 

分 类 号：R455.2[医药卫生—运动医学]