乳腺癌三维超声血管血流参数与Nottingham预后指数的相关性研究  

Correlation between blood flow parameters by three-dimensional sonography and Nottingham prognostic index of breast cancer

作　　者：周军[1] 邹璐璐[1] 陈爱军[3] 刘宇飞[2] 韦力[1] 何勇[1] 

机构地区：[1]三峡大学第一临床医学院 宜昌市中心人民医院超声科,湖北宜昌443003 [2]三峡大学第一临床医学院 宜昌市中心人民医院病理科,湖北宜昌443003 [3]三峡大学第一临床医学院 宜昌市中心人民医院普通外科,湖北宜昌443003

出　　处：《中华超声影像学杂志》2014年第6期511-515,共5页Chinese Journal of Ultrasonography

基　　金：湖北省自然科学基金项目（2011CDB327）

摘　　要：目的探讨乳腺癌三维超声血管血流参数与Nottingham预后指数（NPI）之间的相关性。方法回顾性分析89例经术后病理证实的乳腺浸润性导管癌患者的超声影像资料。术前应用三维彩色能量血管成像技术（3D-CPA）获得血管指数（VI）、血流指数（FI）、血管血流指数（VFI）。NPI根据术后病理资料按公式计算获得。统计不同等级VI、FI、VFI与不同预后等级NPI的病例数，分析各血管血流参数与NPI之间的关系。结果VI与NPI之间相关系数r=0．643（P〈0．0001）。FI、VFI与NPI之间无显著相关性。结论VI与NPI有较好的正相关关系，有助于在术前判断患者预后，为临床确定治疗方案提供依据。Objective To study the eorrelation between blood flow parameters by three-dimensional sonography and Nottingham prognostic index （NPI） of breast cancer.Methods A retrospective analysis of sonographie image data of 89 patients who were pathologically confirmed invasive duetal breast cancer was made.The technology of three-dimensional color power angiography （3D-CPA） was used to obtaining vascular index （VI）, flow index （FI） and vascular-flow index （VFI） before the operation.NPI was obtained by a formula which was computed on a basis of postoperative pathological data.The ease of VI,FI and VFI in different grades and NPI in various prognosis groups were counted, and the relationship between blood flow parameters and NPI was analyzed.Results The correlation coefficient between VI and NPI was 0.643 （P 〈0.0001） and there was no significant correlation between FI, VFI and NPI.Conclusions Among VI and NPI there was a considerable positive eorrelation,VI was helpful to evaluate the prognosis of patients before operation and to provide basis for clinical treatment programs.

关 键 词：超声检查 三维 乳腺肿瘤 Nottingham预后指数 

分 类 号：R737.9[医药卫生—肿瘤]