高强度聚焦超声消融子宫肌瘤供血动脉的治疗价值  

Ablation of feeding-artery with high intensity focused ultrasound in uterine fibroids

作　　者：吴曙军[1] 陈迎祯[1] 伏钢[1] 王文蓉[2] 杨斌[3] 

机构地区：[1]无锡市第二人民医院超声科,214000 [2]无锡市第二人民医院妇科,214000 [3]南京军区南京总医院超声诊断科

出　　处：《中华超声影像学杂志》2014年第6期516-519,共4页Chinese Journal of Ultrasonography

摘　　要：目的评价高强度聚焦超声（HIFU）消融子宫肌瘤瘤体供血动脉对子宫肌瘤的治疗效果。方法选择已生育且确诊子宫肌瘤患者45例，通过彩色多普勒超声及超声造影确定子宫肌瘤的供血动脉位置，应用HIFU进行治疗，观察治疗前后肌瘤内部常规二维、彩色多普勒超声及超声造影、MRI等影像学变化。结果HIFU消融子宫肌瘤供血动脉治疗后，肌瘤体积均有不同程度缩小，治疗区域内彩色血流信号减少或消失；超声造影显示肌瘤平均直径≤5cm组与平均直径〉5cm组相比，肌瘤内无灌注区占肌瘤体积百分比≥70％者比例更高，二者差异有统计学意义。结论HIFU消融子宫肌瘤供血动脉对治疗子宫肌瘤疗效确切。HIFU消融子宫肌瘤供血动脉治疗对于较小的子宫肌瘤疗效较好。Objective To assess the efficacy of high intensity focused ultrasound （HIFU） for the ablation of feeding-artery in uterine fibroids.Methods A total of 45 women with uterine fibroids who had children accepted HIFU treatment.Color Doppler and contrast-enhanced ultrasound were used to target the supply vessels entered the fibroid. HIFU treatment was focused primarily on locations where supplying vessels entered the fibroid.Conventional ultrasound, color Doppler ultrasound, contrast-enhanced ultrasound and MRI were performed before and after HIFU treatment to observe the changes of imaging.Results After HIFU treatment,the volume of uterine fibroids decreased to certain extent.The blood signals decreased or disappeared in the treated regions.Bewteen two groups of the uterine fibroids diamete ≥5 cm and 〈5 cm, there were significant differences in the percentage of the nonperfusion regions in the volume of uterine fibroids （≥70%, P 〈0.05）.Conclusions Ablation of feeding-artery by HIFU is an effective treatment for the uterine fibroids. HIFU treatment is effective for the ablation of feeding-artery in uterine fibroids whose diameter less than 5 cm.

关 键 词：高强聚焦超声消融 子宫肌瘤 

分 类 号：R737.33[医药卫生—肿瘤]