13例以下消化道出血为主要表现的NSAIDs肠病临床分析  

Clinical analysis of NSAIDs associated enteropathy with hemorrhage of lower digestive tract as major performance

作　　者：郭静[1] 孙成都 柴国君[1] 孙刚[1] 郭明洲[1] 

机构地区：[1]中国人民解放军总医院消化内科,北京100853

出　　处：《胃肠病学和肝病学杂志》2014年第6期651-653,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的研究NSAIDs相关性肠病的临床特征,以期提高对其认识,减少漏诊和误诊。方法回顾性分析解放军总医院消化内科13例NSAIDs相关性肠病患者的用药史、临床表现、实验室及影像学检查、胃肠镜检查及治疗。结果 13例NSAIDs相关性肠病均以下消化道出血为主要表现,均有NSAIDs长期服药史,胃镜检查多无异常发现,肠镜检查远端回肠和结肠可见非特异性的黏膜糜烂。停药后,给予PPI、黏膜保护剂可治愈。结论 NSAIDs相关性肠病临床表现及各项检查表现均不典型,易误诊,应结合用药史、临床表现和胃肠镜、胶囊内镜、小肠镜等提高诊断率。Objective To investigate clinical characters of NSAIDs associated enteropathy for the improvement of diagnosis level.Methods The medication history,clinical manifestation,laboratory examination,imagiological examination endoscopic examination and treatment of 13 cases of NSAIDs associated enteropathy patients were analyzed retrospectively.Results Hemorrhage of lower digestive tract was the common and main manifectation.All the patients had a long NSAIDs taking history.There was no specific performance under gastroscope.Non-specific erosion was seen under colonoscope.PPI and mucosa protector were used after the drug withdrawal of NSAIDs to treat this disease.Conclusion The clinical manifestation and examination are not special enough to diagnose NSAIDs associated enteropathy.The medication history,clinical manifestation,endoscope and capsule endoscopy should be combined to improve the diagnosis rate.

关 键 词：NSAIDs相关性肠病 诊断 下消化道出血 

分 类 号：R574[医药卫生—消化系统]