生长抑素对急性胰腺炎患者红细胞指数及微循环状态的影响  

Influence of somatostatin for the erythrocyte indexes and microcirculation state of patients with acute pancreatitis

作　　者：杜宋耿 陈德俊[1] 陈尊发 

机构地区：[1]广东省普宁市普宁华侨医院内一区,广东普宁515300

出　　处：《胃肠病学和肝病学杂志》2014年第6期683-685,共3页Chinese Journal of Gastroenterology and Hepatology

基　　金：广东省普宁市新技术开发项目(c281722)

摘　　要：目的探讨生长抑素对急性胰腺炎患者红细胞指数及微循环状态的影响。方法选取2011年12月-2013年10月广东省普宁市普宁华侨医院内一区收治的80例急性胰腺炎患者为研究对象,将其随机分为对照组(常规急性胰腺炎治疗)40例和观察组(常规治疗加生长抑素)40例,对两组患者治疗前和治疗后第3天和第7天的红细胞指数及微循环状态相关指标进行统计与比较。结果观察组治疗后第3天和第7天的红细胞指数均低于对照组,胰腺血流指标及甲襞微循环等微循环状态相关指标也均优于对照组,差异有统计学意义(P均<0.05)。结论生长抑素对急性胰腺炎患者红细胞指数及微循环状态的影响较大,对胰腺炎患者的疾病状态改善作用明显。Objective To investigate the influence of somatostatin for the erythrocyte indexes and microcirculation state of patients with acute pancreatitis.Methods Eighty patients with acute pancreatitis in the Oversea Chinese Hospital of Puning from Dec.2011 to Oct.2013 were the research object,and they were divided into control group （routine acute pancreatitis treatment group） 40 cases and observation group （routine treatment and somatostatin group） 40 cases by random allocation method,then the erythrocyte indexes and microcirculation state related indexes of two groups before the treatment and at first day and seventh day after the treatment were compared.Results The erythrocyte indexes of observation group at first day and seventh day after the treatment were all lower than those of control group,and the microcirculation state related indexes including the pancreatic blood flow and nailfold microcirculation were all better than those of control group,there were significant differences （P ＜ 0.05）.Conclusion The influence of somatostatin for the erythrocyte indexes and microcirculation state of patients with acute pancreatitis is great,and its improvement role for the disease state of patients with acute pancreatitis is obvious.

关 键 词：生长抑素 急性胰腺炎 红细胞指数 微循环状态 

分 类 号：R576[医药卫生—消化系统]