急性后循环脑梗死动脉溶栓及动静脉联合溶栓的对比分析  

Comparative analysis of arterial thrombolysis and intra-arterial with intravenous thrombolytic treatment of acute posterior circulation stroke

作　　者：信宏[1] 史壮宏[1] 李浩[1] 孙启东[1] 

机构地区：[1]吉化集团公司总医院神经内科,吉林吉林132021

出　　处：《中风与神经疾病杂志》2014年第6期558-559,共2页Journal of Apoplexy and Nervous Diseases

摘　　要：目的比较急性后循环脑梗死动脉溶栓及动静脉联合溶栓的有效性和安全性。方法回顾急性后循环缺血性卒中患者79例,其中动脉溶栓42例,动静脉联合溶栓37例;比较两组血管的再通率以及患者治疗前及治疗后1 h、24 h美国国立卫生院卒中量表(NIHSS)评分。结果单纯动脉溶栓组再通率59.5%,动静脉联合溶栓组血管再通率75.7%;两组患者治疗后1 h、24 h的NIHSS评分和治疗前相比有明显差异(P<0.05),两组之间评分有明显差异(P<0.05)。结论急性后循环脑梗死动静脉联合溶栓可以增加血管的再通率,可以明显改善患者的预后。Objective To compare the efficacy and safety of the arterial thrombolysis and intra-arterial with intravenous thrombolytic treatment of acute posterior circulation stroke. Method We analyzed 79 patients diagnosed as acute posterior circulation stroke retrospectively ,42 of which were treated by arterial thrombolysis while the other 37 by combined intravenous and intra-arterial thrombolysis. Compared the recanalization of blood vessel and the outcome assessment judging by National Institutes of Health Stroke Scale （NIHSS） before and 1 h,24h after thrombolysis. Results The incidence of recanalization of blood vessel was 59.5% ,75.7% respectively in simple arterial thrombolysis group and combined intravenous and intra-arterial thrombolysis group. 1 h,24h after treatment, the NIHSS in patients with combined intravenous and intra-arterial and intravenous thrombolysis were significant different with that of before thrombolysis （ P 〈 0.05 ）. The difference was significant between these two groups（ P 〈 0.05 ）. Conclusion Combined intravenous and intra-arterial thrombolysis treatment can improve the rate of vascular recanalization and improve the patient＇ s prognosis obviously.

关 键 词：动静脉联合溶栓 急性后循环脑梗死 疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]