热解析-高场非对称波形离子迁移谱(FAIMS)技术快速检测合成色素  

Rapid Measurement of Synthetic Pigments by Thermal Desorption-High Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) Technology

作　　者：李娟 赵伟军 李灵锋[2] 李鑫 李鹏[3] 汪小知[2] 

机构地区：[1]苏州微木智能系统有限公司,苏州215000 [2]浙江大学信息与电子工程系,杭州310027 [3]浙江大学苏州工业技术研究院,苏州215163

出　　处：《高等学校化学学报》2014年第7期1403-1408,共6页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:61301046);浙江省公益性技术应用研究计划(批准号:2013C31023);高等学校博士学科点专项科研基金(批准号:20120101110054);江苏省科技支撑计划(社发)(批准号:BE2012655)资助~~

摘　　要：采用热解析-高场非对称波形离子迁移谱（FAIMS）技术快速检测柯衣定、孔雀石绿、罗丹明B和甲基红4种合成色素．通过对热解析温度和载气流量进行优化，确定了不同色素的离子特征信号．在最佳分析条件下，热解析温度为160℃，载气流量为1．6L／min，采用不同模式下补偿电压（CV）值定性，以FAIMS在正模式下检测柯衣定（CV=0．41V）和罗丹明B（CV=-0．89V），在负模式下检测甲基红（CV=-0．67V）和孔雀石绿（CV=0．02V）；用外标法定量检测了样品中的4种合成色素，线性关系R2≥0．9967，检出限为2．5～10μg／L，定量限为5～20μg/L，加标回收率≥78．2％，相对标准偏差RSD≤8％．本文为FAIMS技术快速检测合成色素提供了一定的技术基础．Field asymmetric ion mobility spectrometry （FAIMS） technique was introduced into the sensitive and rapid analysis of four synthetic pigments for the first time. The chrysoidin, malachite green, rhodamine B and methyl red were detected by a co-developed thermal desorption-FAIMS （TD-FAIMS） system. The ion characteristic signals of synthetic pigments were acquired under the optimized conditions with the injection temperature of 160 ℃ and the carrier gas flow rate of 1.6 L/min. Compensation voltage （CV） values with different modes were adopted for qualitative measurement. FAIMS detection signals in positive mode appeared at CV=0. 41 and 0. 89 V for chrysoidine and rhodamine B, respectively, while negative mode detection signals of methyl red and malachite green appeared at CV = 0. 67 and 0. 02 V, respectively. Using external standard method for quantitative measurement, the linear relationship （ R2 ） was above 0. 9967. The limits of detec- tion（LOD） were 2.5--10 μg/L, and limits of quantification （ LOQ ） were 5--20 μg/L, respectively. The average recoveries were higher than 78.2% and the relative standard deviation（RSD） was less than 8.0%. This study laid a foundation for the application of FAIMS technique to rapid detection of synthetic pigments. The FAIMS instrument, which are highly sensitive, simple and fast responsive, demonstrated huge potential in the rapid analysis of synthetic pigments.

关 键 词：高场非对称波形离子迁移谱 合成色素 柯衣定 孔雀石绿 罗丹明B 甲基红 

分 类 号：O656.31[理学—分析化学]