联合检测血清CEA、NSE和SCC对肺癌诊断的临床评价  

作　　者：任波 梁玉玲[2] 

机构地区：[1]成都市武侯区第三人民医院,四川成都610043 [2]成都市第三人民医院,四川成都610031

出　　处：《医学美学美容（中旬刊）》2014年第5期18-19,共2页

摘　　要：目的：评价癌胚抗原（CEA）、神经元特异性烯醇化酶（NSE）和鳞状细胞癌抗原（scc）、对肺癌诊断的临床价值。方法：用化学发光免疫分析法测定93例肺癌和50例良性疾病患者血清CEA、NSE和SCC水平。评价它们对肺癌的诊断价值。结果：肺癌患者血清CEA、NSE和SCC水平显著高于良性疾病（P〈0．05）。三种肿瘤标志物单个检测的灵敏度均小于50％。在肿瘤标志物联合试验中，二种肿瘤标志物联合试验以CEA＋NSE联合的灵敏度最大（64．8％），CEA＋NSE＋SCC联合的灵敏度为70．6％。结论：血清CEA、NSE、SCC联仓检测可提高对肺癌的诊断灵敏度。Objectives To evaluate the clinical values of careinoembryonic antigen （ CEA）, neuron specific enolase （ NSE ）, squamous cell carcinoma antigen （ SCC ） for diagnosis of lung cancer. Methods The levels of serum CEA, NSE and SCC were measured in 93 lung cancer patients and 50patients with benign tung diseases. Results The levels of CEA, NSE and SCC were significantly higher in patients with lung cancer than those in patients with benign lung diseases（ P 〈 0.05 ）. The sensitivity of single test of three tumor markers was less than 50%. The sensitivity of CEA ＋ NSE combination was highest（64.8% ） in two tumor markers combination test, The sensitivity of CEA ＋ NSE ＋ SCC combination was 70.6%. Conclusion The combination measure- ment of serum CEA,NSE and SCC increased the sensitivity for diagnosis of lung cancer

关 键 词：肺癌 癌胚抗原 神经元特异性烯醇化酶 鳞状细胞癌抗原 

分 类 号：R734.2[医药卫生—肿瘤]