康复期双相情感障碍和精神分裂症患者认知功能比较  

The Difference of Cognitive Function between Patients with Bipolar Disorder and Patients with Schizophrenia

作　　者：沈峰[1] 曾友娇 王学林[1] 王玲芝[1] 郭宇恒[1] 

机构地区：[1]中国广州市精神病医院,510370

出　　处：《中国健康心理学杂志》2014年第7期972-974,共3页China Journal of Health Psychology

摘　　要：目的探讨康复期双相障碍和精神分裂症患者认知损害的差异。方法对47例康复期精神分裂症以及37例康复期双相障碍患者进行数字符号、数字广度、连线测验A、B、视觉再生、以及威斯康星卡片分类测试等神经心理测试,对比两组患者在瞬间记忆、短时记忆、图像记忆、注意力以及执行功能等认知功能方面的差异。结果双相情感障碍组数字广度的倒背数(t=2.539,P<0.05)及威斯康星卡片分类测试(WCST)分类个数(t=2.482,P<0.05)多于分裂症组;分裂症组WCST错误数多于双相障碍组(t=-2.298,P<0.05),差别有统计学意义。其中男性双相情感障碍组仅在数字广度的倒背数及总分数多于男性分裂症组(t=2.109,2.014;P<0.05),差别有统计学意义。结论双相障碍患者多方面的认知功能损害小于精神分裂症的患者,提示双相障碍的预后好于精神分裂症。Objective To explore the difference of cognitive deficits between patients with bipolar disorder patients with schizophre -nia.Methods Comparing 47 patients with schizophrenia with 37 patients with bipolar disorder by digit symbol ,digit span,visual repro-duction,trail making test and Wisconsion card sorting test in order to explore the differences of memory ,attention,executive function be-tween two groups .Results The fall back number in digit span ,classification number in Wisconsion card sorting test in patients with bi-polar disorders were higher than those in patients with schizophrenia （t=2.482~2.539）.Patients with schizophrenia had more errors in Winsconsion card than those with bipolar disorder （t=-2.298,P〈0.05）.The scores of male patients with bipolar disorder were higher than male patients with schizophrenia in fall back number and total number in digit span （t=2.109,2.014;P〈0.05）.Conclusion The cognition deficits in patients with bipolar disorder are lower than those in patients with schizophrenia on many aspects ,whichprompts that the prognosis of patients with bipolar disorder is better than that of patients with schizophrenia .

关 键 词：双相情感障碍 精神分裂症 认知功能 注意力 记忆力 执行功能 

分 类 号：R749.4[医药卫生—神经病学与精神病学]