同步放化疗与同步热化疗治疗老年食管癌的疗效比较  

Efficacy Comparison of Concurrent Chemoradiotherapy and Concurrent Thermo-chemotherapy for Elderly Patients with Esophageal Carcinoma

作　　者：刘岑[1] 梁超前[2] 巩合义[2] 

机构地区：[1]邹城市中医院肿瘤科,山东邹城273500 [2]山东省肿瘤医院放疗科,山东济南250117

出　　处：《肿瘤基础与临床》2014年第3期215-217,共3页journal of basic and clinical oncology

摘　　要：目的比较观察同步放化疗与同步热化疗治疗老年食管癌的疗效及毒副反应。方法 78例老年食管癌患者分为放化疗组(40例)和热化疗组(38例)。放化疗组给予放疗联合化疗同步治疗,热化疗组给予热疗联合化疗同步治疗。结果放化疗组与热化疗组有效率分别为90.0%和52.6%(P<0.05);1、2和3 a生存率放化疗组分别为82.5%、50.0%和32.5%,热化疗组分别为39.5%、21.1%和5.3%(P均<0.05)。2组毒副反应均可耐受。结论同步放化疗治疗老年食管癌较同步热化疗在疗效及毒副反应上具有优势。Objective To compare the efficacy and toxicities of concurrent chemoradiotherapy and concurrent thermo-cbemotherapy for elderly patients with esophageal carcinoma. Methods Seventy-eight elderly patients with esophageal carcinoma were divided into two groups. Forty patients of the chemoradiotherapy group were given radio- therapy plus chemotherapy, and 38 patients of the thermo-chemotherapy group were given hyperthermia plus chemo- therapy. Resullts The effective rates of the chemoradiotherapy group and the thermo-chemotherapy group were 90.0% and 52.6% , respectively （ P 〈 0.05 ）. The 1,2, and 3-year survival rates of the chemoradiotherapy group were 82.5% ,50.0% and 32.5% ,respectively;while those of the thermo-chemotherapy group were 39.5% ,21.1% and 5.3 %, respectively（ P 〈 0.05）. The patients of the two groups showed no serious toxicities. Conclusion Con- current chemoradiotherapy for elderly patients with esophageal carcinoma is better than concurrent thermo-chemo- therapy.

关 键 词：放化疗 热化疗 食管癌 

分 类 号：R735.1[医药卫生—肿瘤] R730.58[医药卫生—临床医学]