阑尾类癌3例病理分析  

A clinicopathological analysis of 3 cases of appendix carcinoid tumors

作　　者：姚秀芳[1] 

机构地区：[1]如东县人民医院病理科,江苏226400

出　　处：《交通医学》2014年第3期225-227,共3页Medical Journal of Communications

摘　　要：目的:探讨阑尾类癌的诊断、鉴别诊断、治疗原则及预后。方法:结合文献对3例阑尾类癌的临床资料、病理学形态、免疫表型、治疗方法进行分析并随访。所有标本均经10%中性甲醛固定,石蜡包埋,HE染色,免疫组化采用Envision法。结果:阑尾类癌3例中,临床表现均有右下腹痛。光镜下肿瘤细胞位于粘膜下,瘤细胞分化好、大小较一致、异型性不明显。免疫组化肿瘤细胞Syn+、CgA+、CK20+、Villin+。2例阑尾切除后随访至今未出现复发转移,1例因肿瘤累及回盲部行回盲部切除术后未做任何治疗,随访至今,预后好。结论:阑尾类癌是阑尾常见的恶性肿瘤,对其预后的判断需结合肿块的大小、组织类型、治疗方法,虽预后较好,但仍需对所有的类癌进行长期随访。Objective： To investigate the diagnosis and the d ifferential treatment prognosis of appendix carcinoid tumors. Methods： The clinical data, pathological morphology, and immunophenotype therapeutic methods were analyzed and followed-up in 3 cases of appendix carcinoid tumors. Results： The main clinical manifestation of the 3 cases, 2 cases of male and 1 case of female, mean age 46.5 （17-67）,was the pain right under the lower abdomon. Under the light microscope,tumors were located in the submucus, with good cell differentiation and with the same size without obvious atypia. Immunohistochemical stain showed Syn ＋, CgA＋, CK20＋, and Villin＋ in tumor cells. 2 cases with appendectomy didn’t find recurrence and metastasis during the following-up,and in 1 case with tumor involved in the ileocecus , ileocecal resection was performed,and up to now the prognosis of this case is good. Conclusion： Appendiceal carcinoid tumor is a common malignant tumor of the appendix and the evulateing prognosis requires to be made in combination with the size of the mass, the histological type, and the treatment method, although the prognosis is good, long-term follow-up is still needed for all types of carcinoid tumors.

关 键 词：阑尾类癌 杯状细胞腺类癌 免疫组织化学法 

分 类 号：R735.36[医药卫生—肿瘤]