含取代噻吩环吡啶酰胺分子的微波合成与光谱表征  

Microwave irradiated synthesis and spectral analysis of pyridine amide with the thiophene ring substituent

作　　者：罗世霞[1] 陈晓靓[2] 朱淮武[1] 张晓丽[3] 卫钢 

机构地区：[1]贵州师范大学化学与材料科学学院,贵州贵阳550001 [2]贵阳护理职业学院,贵州贵阳550081 [3]贵州省地质矿产中心实验室,贵州贵阳550004 [4]CSIRO Materials Science and Engineering, PO Box 218, Lindfield, NSW 2070, Australia

出　　处：《化学研究与应用》2014年第6期855-859,共5页Chemical Research and Application

基　　金：教育部春晖计划合作科研项目(Z2011040)资助

摘　　要：利用无溶剂微波合成法制备了两种新颖的取代噻吩基修饰吡啶酰胺分子吡啶-2,6-二[N-(2'-噻吩基甲基)甲酰胺](L1)和吡啶-2,6-二[N-(2'-噻吩基乙基)甲酰胺](L2),其合成过程无需溶剂,反应速度快,操作简单,节能环保。通过元素分析、1H-NMR、13C-NMR、IR及UV等表征手段对目标化合物L1和L2的分子结构进行了确认,对化合物的核磁谱线、红外特征吸收峰及紫外最大吸收峰进行了归属分析,丰富了吡啶酰胺类化合物的光谱数据。Two novel pyridine amide molecules with the thiophene ring substituent,2,6-bis[N-（2′-thienylmethyl）carbamoyl]pyri-dine（L1）and 2,6-bis[N-（2′-thienylethyl）carbamoyl]pyridine（L2）,were synthesized under microwave irradiation in a solvent-free condition. It demonstrated the synthesis methods as a reaction with free of solvent,fast,simple operation,safe,low energy consump-tion and environmental friendly. The target products L1 and L2 were characterized by elemental microanalysis,1 H＆amp;13 C NMR,FT-IR and UV. The nuclear magnetic spectral bands,the main infrared absorption peaks and the ultraviolet maximum wavelength of the compounds were assigned. The spectroscopic analytical results in enriching the spectral properties data of pyridine amides.

关 键 词：吡啶酰胺 噻吩环 微波合成 光谱性质 

分 类 号：O626.3[理学—有机化学]