肺腺、鳞癌肿瘤大小对纵隔淋巴结转移的影响  

Effects of size of pulmonary adenocarcinoma squamous carcinoma tumor on mediastinal lymphonode metastasis

作　　者：郭怀龙[1] 高文[1] 郑卉[1] 陈昶[1] 

机构地区：[1]上海市肺科医院,200433

出　　处：《中华医学杂志》2014年第23期1801-1803,共3页National Medical Journal of China

摘　　要：目的：本研究旨在研究肺鳞癌、腺癌肿瘤的大小对淋巴结转移的不同相关性，并且阐明与纵隔淋巴结转移高发相关的肿瘤大小的临界值。方法回顾性分析上海市肺科医院2005至2006年间1346例经外科手术切除及纵隔淋巴结清扫的直径＜8 cm的肺原发性鳞、腺癌，分析肿瘤组织类型、大小与纵隔淋巴结转移相关性，以及腺、鳞癌肿瘤大小与淋巴解转移的不同结果。结果直径在2.0～2.4 cm的腺癌是淋巴结转移的危险度增加的节点，直径＞2 cm的腺癌中43％～63％，发生纵隔淋巴结转移（P＜0.01）。而在肺鳞癌中未发现这些现象（P＞0.05）。结论肺腺癌肿瘤的大小与纵隔淋巴结转移有显著相关，而肺鳞癌大小与纵隔淋巴结转移相关性不大。Objective To explore the relationship between primary tumor size and mediastinal nodal metastases among different cell types in non-small cell lung cancer （ NSCLC） and clarify the cutoff size for a higher likelihood of metastases.Methods Retrospective evaluations were conducted for 1 346 NSCLC patients from January 2005 to January 2006.Primary focus was placed upon cases with primary tumor size 〈8.0 cm.Results It was shown that 2.0 cm was the critical cutoff size for increased mediastinal nodal metastases in adenocarcinoma （ P〈0.01 ） , but not in squamous cell carcinoma （ P〉0.05 ）.Conclusion Tumor size matters differently in pulmonary adenocarcinoma and squamous cell carcinoma.

关 键 词：癌 非小细胞肺 淋巴转移 癌 鳞状细胞 

分 类 号：R734.2[医药卫生—肿瘤]