血清中性激素水平与视网膜静脉周围炎的关系  被引量:6

Serum sexual hormone level and Eales disease

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作  者:左炜[1] 王恒[1] 祝芸芸[1] 周金文[1] 

机构地区:[1]深圳市第四人民医院眼科,218033

出  处:《临床眼科杂志》2014年第3期248-249,共2页Journal of Clinical Ophthalmology

摘  要:目的探讨血清中性激素水平与视网膜静脉周围炎(Eales病)发病的关系。方法回顾分析经临床表现、眼底检查及荧光素眼底血管造影(FFA)确诊为Eales病的76例患者的临床资料。同时选取与Eales病患者年龄、性别相匹配的76例体检健康者作为对照组。抽取两组受试者肘静脉血,用化学发光法检测Eales例患者及对照组血清中部分性激素:促黄体生成素(LH)、促卵泡生成素(FSH)、睾酮(T)含量。采用t检验对检测结果进行统计学处理。结果与对照组相比,Eales病组患者血清中性激素值均升高,其差异有统计学意义。结论性激素水平与Eales病的发病是有关联的,血清LH、FSH、T指标的变化可作为Eales病患者的一个参考指标。Objective To investigate the relationship between Eales disease and serum sexual hormone level . Methods Seventy-six cases of Eales disease were reviewed .Clinical presentations , fundus examination and fundus fluo-rescein angiography ( FFA) results were retrospectively analyzed .Another 76 healthy, age and gender matched subjects were selected as control .Sexual hormones , including luteinizing hormone ( LH) , follicle stimulating hormone ( FSH) and testosterone were measured in both groups using chemiluminescence methods .T-test was used to detect differences between the two groups .Results Sexual hormone levels were significantly higher in patients with Eales disease than in control sub -jects.Conclusion Sexual hormones can be associated with Eales disease .Chanes in serum LH , FSH or testosterone can be used as biomarkers for Eales disease .

关 键 词:视网膜静脉周围炎 促黄体生成素 促卵泡生成素 睾酮 

分 类 号:R774.1[医药卫生—眼科]

 

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