后发性白内障防治进展  

Prevention and treatment of posterior capsular opacification after cataract surgery

作　　者：万修华[1] 李晓霞[2] 

机构地区：[1]首都医科大学附属北京同仁医院北京同仁眼科中心眼科学与视觉科学北京市重点实验室北京市眼科研究所,100005 [2]郑州市第二人民医院眼科,450006

出　　处：《国际眼科纵览》2014年第3期180-184,共5页International Review of Ophthalmology

摘　　要：晶状体后囊膜混浊（posterior capsular opacification,PCO）也称后发性白内障,是白内障术后最常见的并发症.对其防治,以往研究多关注在白内障设备、操作技巧、IOL材料及设计方面,且已日臻完善.近些年更多关注PCO相关癌基因、凋亡基因等,但操作相对复杂,仅处于基础研究阶段;通过免疫手段干扰PCO发生,相对简单、廉价、可行,但效应短暂;药物治疗具有潜在的细胞毒性作用.Posterior capsular opacification（PCO） remains the most common postoperative complication after cataract surgery.Previous studies had focused on improvements in surgical instruments and techniques,novel IOL biomaterials and IOL designs,and had been well developed.Lately more and more studies focused on cancer and apoptosis gene research which were much complex and only at a basic research stage.Using immunological techniques interfered PCO which were simply,cheap and feasible.And medical drugs for PCO which had potential cytotoxicity.

关 键 词：晶状体后囊膜混浊 上皮间质转化 基因 免疫 

分 类 号：R776.1[医药卫生—眼科]