无水乙醇硬化治疗囊性和囊性为主甲状腺结节疗效比较及其影响因素  

Ethanol ablation of cystic and predominantly cystic thyroid nodules:Analysis of efficacy and related factors

作　　者：陈少华[1] 吕国荣[1,2] 李伯义[1] 

机构地区：[1]福建医科大学附属第二医院超声科,福建泉州362000 [2]泉州医学高等专科学校,福建泉州362000

出　　处：《中国介入影像与治疗学》2014年第7期407-410,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的比较无水乙醇硬化治疗囊性及囊性为主甲状腺结节的疗效,分析其影响因素。方法回顾性分析148个接受超声引导无水乙醇硬化治疗的囊性及以囊性为主甲状腺结节,以结节缩小>50%作为依据判定疗效,分析影响疗效的相关因素。结果硬化治疗6个月后,甲状腺结节平均体积从(16.83±14.04)ml缩小至(2.44±1.32)ml,平均缩小率为(85.83±8.64)%,有效率为90.54%(134/148);囊性甲状腺结节的疗效优于囊性为主甲状腺结节(95.41%vs76.92%,P<0.05)。结节初始体积、实性成分和血供情况是影响硬化治疗效果的独立影响因素。结论无水乙醇硬化治疗囊性和囊性为主甲状腺结节均有效,对囊性结节治疗效果最佳,而对体积较大及血供丰富的囊性为主甲状腺结节疗效较差。Objective To compare the efficacy of ethanol ablation （EA） for cystic and predominantly cystic thyroid nodules, and to explore the related factors. Methods A total of 148 thyroid nodules treated with EA were analyzed retrospectively. Taking volume reduction rate of nodules 〉50% as standard, efficacy of EA for cystic and predominantly cystic nodules was compared. The factors related to EA efficacy, including patient＇s sex, age, as well as initial volume, solid component, vascularity and fluid nature of nodules were evaluated. Results Six months after treatment, the mean volume of nodules decreased from （16.83±14. 04）ml to （2.44±1.32）ml, the mean volume reduction rate was （85.83±8.64）%, and the therapeutic success rate was 90. 54%（134/148）. EA was more effective for cystic than that for predominantly cystic nodules （95.41% vs 76.92%）. The initial volume, solid component and vascularity of nodules were independent impact predictors of EA efficacy. Conclusion EA is effective for both cystic and predominantly cystic nodules, especially for the former, but is less effective in large or vascular predominantly cystic nodules.

关 键 词：甲状腺结节 硬化疗法 超声检查 乙醇 治疗结果 

分 类 号：R736.1[医药卫生—肿瘤] R445.1[医药卫生—临床医学]