苯并(a)芘对大弹涂鱼肝脏和卵巢还原型谷胱甘肽含量影响的比较研究  

Effect of benzo(a) pyrene on contents of reduced-glutathione in the liver and ovary of Boleophthalmus pectinirostris

作　　者：冯涛[1] 郑微云[1] 陈荣[1] 

机构地区：[1]国家教委海洋生态环境开放研究实验室/厦门大学环境科学研究中心,福建厦门361005

出　　处：《海洋环境科学》2001年第1期12-15,共4页Marine Environmental Science

基　　金：国家自然科学基金资助项目!(49876 0 2 9);福建省自然科学基金资助项目!(C9810 0 0 3)

摘　　要：分析了大弹涂肌肉、鳃、肝脏、内脏 (不含肝脏 )以及卵巢等不同器官的还原型谷胱甘肽含量 ,并以还原型谷胱甘肽含量较高的肝脏和卵巢为研究对象 ,在实验生态条件下 ,将大弹涂鱼暴露于 0 ,0 .0 5 ,0 .2和 0 .5mg/L等不同浓度的苯并 (a)芘 3d ,比较这两个器官中还原型谷胱甘肽含量的变化。结果显示 ,苯并 (a)芘胁迫下 ,大弹涂鱼肝脏和卵巢还原型谷胱甘肽含量均显著升高 (P≤ 0 .0 5 ) ;表明肝脏和卵巢都是代谢苯并 (a)芘的主要器官 ,还原型谷胱甘肽含量的显著升高表明机体对苯并 (a)芘胁迫的适应性反应。The contents of GSH in different organs of tissues such as musle, gill, liver, viscera(exclude the liver) and ovary in Boleophthalmus pectinirostris were measured. The changes of GSH content in the liver and ovary in which the GSH contents were much higher than the others, had been compared in condition of experiment after fishes were exposed to BaP at concentration of 0, 0.05, 0.2 and 0.5 mg/L respectively for 3 d. The results show that the contents of GSH in the liver and ovary of Boleophthalmus pectinirostris change significantly ( P ≤0.05). It turns out that both the liver and the ovary are the key organ in metabolism of BaP. The increased level of GSH may represent an adaptive response to BaP exposure.

关 键 词：苯并(A)芘 大弹涂鱼 还原型谷胱甘肽 肝脏 卵巢 环境污染 

分 类 号：X171.5[环境科学与工程—环境科学] X174