肝硬化病人消化性溃疡和门脉高压性胃病的发生及特点  

Peptic ulcer and portal hypertensive gastrosis in patients with liver cirrhosis

作　　者：庹必光[1] 石国庆[1] 周稻菽[1] 赵逵[1] 文学铨[1] 

机构地区：[1]遵义医学院附属医院消化科,563003

出　　处：《贵州医药》2001年第4期316-317,共2页Guizhou Medical Journal

摘　　要：目的研究肝硬化病人消化性溃疡和门脉高压性胃病的发生及临床特点。方法以1990年 1月～ 1999年 4月间在我院住院的 496例病人为研究对象作胃镜检查。结果肝硬化消化性溃疡的发生率为 14 92 % ,门脉高压性胃病的发生率为 43 75 % ;在childA级、B级、C级肝功能病人之间消化性溃疡和门脉高压性胃病的发生率差异无显著意义 (P >0 0 5 ) ;有门脉高压性胃病和食道静脉曲张者消化性溃疡的发生率明显高于无门脉高压性胃病和食道静脉曲张者 (P <0 0 1)。肝硬化病人消化性溃疡 82 43 %无症状。结论门静脉高压可能是肝硬化病人消化性溃疡发生率增高的重要致病因素 ,肝硬化病人消化性溃疡绝大多数无症状。Objective To investigate the occurrence and clinical characteristics of peptic ulcer and portal hypertensive gastrosis in patients with liver cirrhosis.Methods A retrospective investigation was performed in 496 inpatients with liver cirrhosis from January 1990 to April 1999 who have been examined by gastroscope.Results The incidence of peptic ulcer in cirrhosis patients was 14.92%, and portal hypertensive gastrosis was 43.75%. The incidences of peptic ulcer and portal hypertensive gastrosis showed that no statistical differences between patients with child's A, child's B and child's C ( P >0.05). The incidences of peptic ulcer in patients with portal hypertensive gastrosis (21.20%) and esophageal varices (16.71%) were markedly higher than that in patients without portal hypertensive gastrosis (10.04%) and esophageal varices (7.37%) (P<0.01). 82.43% of peptic ulcer in the patients with liver cirrhosis were asymptomatic.Conclusion Portal hypertension is an important pathogenic factor in high prevalence of peptic ulcer in cirrhostic patients. The most of cirrhotic patients with peptic ulcer is asymptomatic.

关 键 词：肝硬化 消化性溃疡 门脉高压性胃病 临床特点 

分 类 号：R575.2[医药卫生—消化系统] R573.1[医药卫生—内科学]