孔源性视网膜脱离中视网膜下液维生素E和A含量及与服药关系  

Levels of vitamin E and A of subretinal fluid in rhegmatogenous retinal detachment and after oral treatment

作　　者：朱晓华[1] 姜德咏[1] 聂爱光[1] 

机构地区：[1]湖南医科大学第二附属医院眼科,长沙410011

出　　处：《眼科》2001年第1期26-28,共3页Ophthalmology in China

摘　　要：目的 :研究维生素E和维生素A在视网膜下液 (SRF)的含量 ,并观察服用维生素E和C对其含量的影响。方法 :用微量荧光测量法测定 5 6例孔源性视网膜脱离患者的SRF及血清中维生素E和A的含量 ,其中 18例术前服用维生素E和C各 6 0 0mg/d。结果 :SRF中含有维生素E和A ,二者呈显著正相关 (r=0 495 ,P≤ 0 0 5 ) ,与病程也呈正相关 (r=0 380 ,P≤0 0 5 )。服药患者血清及SRF的维生素E水平显著高于未服药者 (P≤ 0 0 5 ) ,服药 3天后SRF的维生素E水平方显著升高(P≤ 0 0 5 )。结论 :视网膜脱离后仍能动员自身组织的抗过氧化的保护作用 ,服用维生素E和C可以提高SRF中抗过氧化物水平 。HT5”SS][WT5”BZ][ST5”BZ]Objective:To study the change of the levels of vitamin E and A of subretinal fluid(SRF) in rhegmatogenous retinal detachment(RRD),and the effect of oral treatment with vitamin E and A Mathod:To assay the levels of vitamin E and A of SRF and serum in 38 patients with RRD,and 18 patients with vitamin E and C 600mg orally per day Results:There are vitamin E and A in SRF of RRD The levels of vitamin E is significantly related to vitamin A in SRF and course of RRD (r 1=0 495 P≤0 00,r 2=0 380 P<0 05),and significantly higher in treatment group than non treatment group (P≤0 05) The contents of vitamin E in SRF are singnificantly increased(P≤0 05)in patients with 3 days’treatment more Conclusions:The results show that retinal tissus still can release antioxidant protective substances such as vitamin E and A after detachment Treatment with vitamin E and C can increase the contents of antioxidant in SRF and contribute additional neuroprotective agents for detached retinal tissues [HT5”H][WT5”HZ][ST5”HZ]

关 键 词：视网膜下液 化学 维生素E 维生素A 

分 类 号：R774.1[医药卫生—眼科]