脑瘫患儿脑室周围白质软化症的MRI特征探讨  

MRI features of periventricular leukomalacia in children with cerebral palsy

作　　者：林珊[1] 徐建民[1] 孙进[1] 温民生[1] 张红[1] 

机构地区：[1]中国康复研究中心北京博爱医院影像科,北京市100077

出　　处：《中国康复理论与实践》2001年第1期21-22,25,共3页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的探讨脑瘫儿童脑室周围白质软化症 (PVL)的MRI表现特点。方法回顾性分析 83例缺氧缺血性脑病导致PVL的脑瘫患儿 (其中早产 2 3例 )的临床资料和MRI表现。结果①PVL导致脑瘫儿童的MRI表现 :脑白质减少主要发生在侧脑室三角区 体部周围及半卵圆中心 ;脑白质信号异常主要发生在侧脑室三角区、体部周围和半卵圆中心 ;脑室扩大变形 ;脑沟裂池扩大增宽 ;胼胝体异常。其他MRI的异常表现为脑皮层萎缩软化和基底节变性。②早产儿和足月儿PVL的不同MRI特点 :早产儿和足月儿在脑白质区出现长T1、明显长T2信号的软化、囊变灶和脑室变形 (脑室边缘凹凸不平 )等均有显著性差异。结论MRI可清晰显示脑瘫患儿PVL的MRI特点、病变程度、范围以及早产儿与足月儿PVL的不同之处。早产儿发生PVL的程度较足月儿重 ,易出现侧脑室旁脑白质的长T1、明显长T2信号的软化、囊变灶及侧脑室不规则扩大。ObjectiveTo study the MRI features of children with cerebral palsy(CP) resulting from anoxia.Methods The clinical and MRI findings in 83 premature or mature children affected by cerebral palsy resulting from PVL were reviewed retrospectively to search for the MRI features and the data were analyzed by statistic. Results1. MRI features of CP children resulting from anoxia were clearly demonstrated:1) MRI features of PVL: reduction of white matter ;T2W signal hyperintensity in white matter; ventricle enlarged or irregular appearance; lateral fissure;deepened or widened Sulci;and abnormal corpus callossum; 2) other abnormal MRI features: basal ganglion damaged; cerebral cortex atrophy or malacia. 2.Differences in MRI features between premature and mature CP children: there are significant differences between premature and mature children at malacia and cyst of deep white matter; enlargement and irregularity of the lateral ventricles. ConclusionsMRI examination can clearly display the level and scope of focus of PVL,and the differences in MRI features between premature and mature children.The level and degree of premature children are deeper and more extensive than those of mature children.Cyst and malacia in deep white matter,enlargement and irregularity of the lateral ventricles occur more frequantly in premature children.

关 键 词：脑瘫 脑室周围白质软化 磁共振成像 

分 类 号：R742.3[医药卫生—神经病学与精神病学]