糖皮质激素滴眼液对PRK疗效及并发症的影响  

Effects of corticosteriod on the outcome and complication of PRK

作　　者：邓应平[1] 王琳[1] 蔡如超[1] 申光琴 

机构地区：[1]华西医科大学第一附属医院眼科,成都610041

出　　处：《眼科研究》2001年第1期67-69,共3页Chinese Ophthalmic Research

摘　　要：目的探讨不同糖皮质激素滴眼液及不同使用方法对准分子激光屈光性角膜切削术（ＰＲＫ）疗效的影响，分析ＰＲＫ术后因使用糖皮质激素滴眼液而致高眼压的发生、发展情况及防治措施。方法分析分别使用地塞米松、爱氟龙和拂炎的３组ＰＲＫ术后病人，在术后３月内视力、屈光度、眼压及角膜混浊情况并进行统计学处理。结果地塞米松及拂炎滴眼液比爱氟龙抑制角膜增生的作用稍强，但无统计学意义；地塞米松和拂炎滴眼液引起皮质类固醇性高眼压的比例较爱氟龙高，具有统计学差异。不同的个体对相同的糖皮质激素滴眼液的反应有一定的差异。结论ＰＲＫ术后糖皮质激素滴眼液的使用对维持手术疗效十分重要。不同的糖皮质激素滴眼液对ＰＲＫ术后角膜增生的抑制作用以及引起皮质类固醇性高眼压的比例不同；ＰＲＫ术后应根据不同情况选择糖皮质激素滴眼液及不同的使用时限。Objective To evaluate the effects of corticosteriods on the result and complications after PRK. Methods All of the cases were divided into three groups based on the use of Dexmethason, Florex, and fluorometholone. The visual acuity, refraction,intraocular pressure and haze were analyzed in three months after PRK. Results The effects of Dexmethason and Flurex on the haze'were stronger than that of fluomethason. The incidence of high intraocular pressure in dexmethason and flurex groups were higher than that of fluomethason. The effects of corticosteriod had individual difference. Conclusion it is very important to choose the different corticosteriods according to the different Condition.

关 键 词：糖皮质激素滴眼液 皮质类固醇性高眼压 准分子激光屈光性角膜切削术 PRK 并发症 

分 类 号：R779.63[医药卫生—眼科]