脑出血和脑梗塞急性期血浆皮质醇变化及其与病情和预后的关系  

Change of Plasma Cortisol of Patients with CH and CI in Acute Stage and Its Relation with Condition and Prognosis

作　　者：钟庆风 胡维铭[1] 朱雨岚[1] 郑雅文[1] 何树庄[2] 葛兰波[2] 朱秀英[2] 

机构地区：[1]哈尔滨医科大学二院神经科 [2]哈尔滨医科大学二院临床药学药物研究所

出　　处：《哈尔滨医科大学学报》1991年第3期178-181,共4页Journal of Harbin Medical University

摘　　要：本文对60例脑出血及25例脑梗塞病人急性期血浆皮质醇含量进行了测定并与31例正常人对照,结果表明脑梗塞病人与正常人无明显差异;脑出血组则明显高于脑梗塞组。脑出血病人病情越重含量越高,脑出血极重型血浆皮质醇含量高于1380nmol/L。11例含量在1987nmol/L以上者全部死亡。脑出血1周后随病情好转血浆皮质醇含量明显下降者均存活;含量持续增高者预后不良。可见血浆皮质醇测定有助于判定急性脑血管病患者(尤其是脑出血)的病情和预后。The content of plasma cortisol was determined in 60 patients with cerebral haemorrhage(CH)and 25 patients with cerebral infarction(CI) in acute stage and compared with those of 31 normal subjects. The results showed that no difference was found between patients with CI and normal group, but the content of cortisol in patients with CH was much higher that in patients with CI . In CI group, the more the condition was serious, the more the content of the plasma cortisol was higher. The content of corticosteroid decreased obviously when the patients got better. On the other hand, the prognosis would be bad when the cortsol increased continuously. Therefore the determined of plasma cortisol is helpful to the judgement of the condition and prognosis of acute cerebrovascular diseases, especially CH.

关 键 词：脑出血 脑栓塞 氢化可的松 

分 类 号：R743.302[医药卫生—神经病学与精神病学]