放免法测定血清T3、T4对白血病预后的判断  

ALTERATION OF SERUM T3 AND T4 CONCENTRATION IN LEUKEMIA PATIENTS: AN ANALYSIS OF 63 CASES

作　　者：顾桂兰[1] 陈唤青[1] 杨锦媛[1] 

机构地区：[1]南通医学院附属医院内科

出　　处：《南通医学院学报》1991年第4期304-306,358,共3页ACTA Academiae Medicinae Nantong

摘　　要：报道63例白血病患者血清T3、T4浓度动态检测的结果。发现急性白血病常见T3降低，T4正常。终末期T3多明显降低，少数同时合并T4降低。慢性白血病的慢性期T3、T4均正常，急变后T3降低，终末期T3、T4降低，T3持续低于正常值则完全缓解（CR）率低，生存期短，病死率高，而T3持续正常或仅初次降低者则CR率高，病死率低，若CR期T3低于正常值以下预示疾病复发，再诱导治疗过程中T复升至正常且持续保持者，则再次CR的成功率高。We investigated the alteration of serum T_3 and T_4 during the courses of 63 leukemia patients. The result showed that serum T_3 and T_4 concentration often decreased in acute leukemia patients. Serum T_3 levels were decreased in almost all end-stage patients. While serum T_4 levels decreased only in some ones. The life span was shorter and the mortality was higher in the patients whose decreased serum T_3 levels were persistant. The rate of complete, remission was high in the patients whose serum T_3 concentration were in normal range. The lowering of serum T_3 levels below normal range in complete remission period indicated the relapse of disease, In these patients the rate of complete remission was also high if the concentration of serum T_3 was increased during the re-inducing theraputic period.

关 键 词：甲状腺激素 T3 T4 白血病 预后 

分 类 号：R733.707[医药卫生—肿瘤]