麦胚抗动脉粥样硬化实验研究  

THE EXPERIMENTAL STUDY ON THE ANTIATHEROSCLEROSIS EFFECT OF WHEAT GERM

作　　者：李绍忱[1] 郝培良[1] 王永杰[1] 钱晓涛[2] 徐贵发[3] 秦怀金[1] 

机构地区：[1]山东医科大学流行病学教研室 [2]山东医科大学毒理学研究室 [3]山东医科大学营养与食品卫生学教研室

出　　处：《山东医科大学学报》1990年第1期18-21,共4页Acta Academiae Medicinae Shandong

摘　　要：雄性鹌鹑高脂饲料喂养45d可形成典型的动脉粥样硬化病变。给予麦胚每只10g/d具有明显的抗动脉粥样硬化作用,表现体重增加,生理活动增强,降低血清胆固醇,显著增高HDL-C,其抗动脉粥样硬化作用优于烟酸肌醇酯(每日2.5mg/100g体重),且无药物所致进食减退、体重减轻、肝脏脂肪变性等副作用。实验表明麦胚是一种理想的有前途的抗动脉粥样硬化食品。The male quails fed by hyper fat forage could form the typi-cal model of atherosclerosis within 45 days that is the experimental foun-dation of this study.The wheat germ 10g/day for each quail has remarka-blebly antiatherosclerosis effect,which shows the increase in body weight,the promotion of physiological activities,significant decrease of cholesterol,the increase of HDL-C and the lower of the athcrsclerogenic index(TC/HDL-C).As the result,the antiatherosclerosis effect of wheat germ is obvious-ly stronger than that of Inosital Hexanicotinate.Although the Inosital Hexanicotinate can also decrease the Ievel of TC,it injure the liver,fatty denaturation,and cause other side effect ef digestive system such as ano-rexia,salivation,etc.The wheat germ as a food has potential for prevention of cardio-cerebro vascular diseases.

关 键 词：麦胚 动脉粥样硬化 抗胆甾醇血症剂 鹌鹑 治疗 

分 类 号：R543.505[医药卫生—心血管疾病] R972.6[医药卫生—内科学]