仪器中子活化分析法研究脑缺血后脑中的元素含量  

Study on elemental contents in rabbit brain after cerebral ischemia by INAA

作　　者：王荫淞[1] 赵惠芳[2] 张天锡[2] 谈明光[1] 庄圭荪[1] 陈宝林[3] 田恒力[2] 孙青芳[2] 

机构地区：[1]中国科学院上海原子核研究所,上海201800 [2]上海第二医科大学,上海200025 [3]上海市计量测试技术研究院,上海200233

出　　处：《核技术》2001年第3期184-188,共5页Nuclear Techniques

基　　金：国家自然科学基金! (19475 0 6 2 )

摘　　要：建立了兔局灶脑缺血模型。用仪器中子活化分析法测定了该动物模型脑组织中的锌、硒、镁、锰、钠、钾和氯的含量 ,并以正常兔脑组织作对照。结果表明 ,某些元素的含量在脑缺血后有显著变化 ,并随时间而变。还观察到一些元素的含量在左右两个半脑间的相关性以及钠和氯含量之间的相关性。用中药治疗脑缺血病是很有效的。将两种新的中药用于脑缺血兔 。Cerebral ischemia is a serious cerebral vascular disease. In this work, the cerebral ischemia model of rabbit was established through operation. The elemental contents of Zn, Se, Mg, Mn, Na, K and Cl in rabbit brain tissues were determined by instrumental neutron activation analysis (INAA). The results show that some elemental contents change obviously after cerebral ischemia and change with time. The correlation of some elemental contents between left and right brain tissues was observed, and the correlation between Na and Cl contents in brain was also observed.Traditional chinese medicine is effective to cure cerebral ischemia. Two new Chinese medicines were applied to rabbits with cerebral ischemia, and their influence on elemental contents were observed.

关 键 词：脑缺血 元素含量 仪器中子活化分析 兔脑组织 中药 治疗 病理 水蛭类药物 

分 类 号：R743[医药卫生—神经病学与精神病学] R277.73[医药卫生—临床医学]