参仙升脉液对实验性病态窦房结综合征的作用研究  

Research on the Effect of Shen Xian Sheng Mai Ye(参仙升脉液)on Experimental Sick Sinus Syndrome

作　　者：许树强[1] 武泽民 史载祥[1] 马金莲[2] 施雪筠[2] 龙致贤[2] 刘爱挛 杨树芳 

机构地区：[1]中日友好医院,北京100029 [2]北京中医学院

出　　处：《中西医结合杂志》1991年第11期674-675,共2页

摘　　要：本研究用日本大耳白兔75只,平均分为5组,即参仙升脉液三个不同剂量组和阿托品、葡萄糖两个对照组。用20%甲醛外敷窦房结区造成病态窦房结综合征的动物模型,观察心率变化,心律失常情况和心电生理指标,结果表明参仙升脉液可以明显提高窦性心率,纠正心律失常以及改善窦房结功能。The effects of Shen Xian Sheng Mai Ye(SXSMY)on experimental sick sinus syndrome(SSS) were observed.By applying 20% formaldehyde to the rabbits' sino-atrial node area,we got the acute animal model of SSS.By observing the rabbits' heart rate(HR),arrhythmia and cardioelectric physiologic index in different periods,the results were as follows:(1)Increasing heart rate:SXSMY could increase rabbits'HR 10～30 times per minute by observing electrocardiogram within 2 hours (P<0.05～0.001).(2)Correcting arrhythmia:SXSMY could reduce arrhythmia of sinus nodal arrest and nodal rhythm remarkably.(3)Improving sinus atrial node function:SXSMY could improve sinus node recovery time (SNRT) and sinus atriaI conducting time (SACT) with the method of atrial pacing (AP) (P<0.01～0.001).But the above results did not appear in atropine and glucose groups.

关 键 词：参仙升脉液 实验性病态窦房结综合征 心电图 心电生理指标 中医药治疗 

分 类 号：R259.417.4[医药卫生—中西医结合] R285.5[医药卫生—中医内科学]