黄芪增免散对围手术期食管癌间质反应的影响  

Effect of Huangqi Zengmian Powder on Interstitial Response in Patients with Esophageal Cancer at Peri-Operational Period

作　　者：高新平[1] 赵卫星[1] 张志亮[2] 刘彩莉[2] 李汉臣[2] 杜华贞[1] 杨廷桐[1] 

机构地区：[1]新乡医学院病理学教研室,河南453003 [2]新乡医学院第一附属医院

出　　处：《中国中西医结合杂志》2001年第3期171-173,共3页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：河南省教委科研基金

摘　　要：目的 :观察黄芪增免散对围手术期食管癌间质反应的影响。方法 :用黄芪增免散治疗围手术期食管癌患者 37例 ,共 4周。采用甲苯胺蓝染色方法 ,对手术切除标本进行组织学观察用药后食管癌间质(包括肥大细胞、微血管和淋巴细胞 )反应的变化 ,并与同期手术治疗的 14例患者作对照。结果 :与对照组比较 ,治疗组食管癌间质肥大细胞数量和淋巴细胞灶状聚集增多 ,间质微血管损伤现象明显 (P <0 0 1)。结论 :黄芪增免散对围手术期食管癌患者免疫功能有改善作用。Objective: To observe the effect of Huangqi Zengmian Powder (HQZMP) on interstitial response of esophageal cancer at peri operational period. Methods: Thirty seven patients of esophageal cancer were treated with HQZMP for 4 weeks peri operationally. The pathological interstitial changes (including mastocyte, microvessels and lymphocytic response) in resected esophageal cancer sample were observed using toluidine blue stain. Results: As compared with the non HQZMP treated control group, quantity of interstitial mastocyte, focal lymphocytic aggregation and interstitial microvessel damage in the HQZMP treated group were more obvious (P<0 01). Conclusion: HQZMP could improve the immune function of esophageal patients in peri operational period.

关 键 词：黄芪增免散 食管癌 间质反应 肥大细胞 免疫功能 围手术期 中医药疗法 

分 类 号：R735.1[医药卫生—肿瘤]