鼻咽癌远处转移281例的临床分析  

Clinical Study on Distant Metastasis of Nasopharyngeal Carcinoma:A Report 281 Cases

作　　者：许德明[1] 陈国权[1] 李声谊[1] 陈焕伟[1] 蔡永广[1] 林坚[1] 凌华海[1] 

机构地区：[1]广东省农垦中心医院肿瘤内科四区,广东湛江524002

出　　处：《河南肿瘤学杂志》2001年第2期99-100,共2页Henan Journal of Oncology

摘　　要：目的　探讨鼻咽癌远处转移的规律和治疗方法。方法　对 2 81例鼻咽癌远处转移的临床资料进行回顾性分析。结果　鼻咽癌远处转移率 2 0 3% (2 81/ 1383) ,其中肺转移 42 7% (12 0 / 2 81) ,骨转移 32 4% (91/ 2 81) ,肝转移 2 1 4% (6 0 / 2 81) ,放疗后 1～ 2年发生转移 47 7% (134 / 2 81)。结论　大部分鼻咽癌远处转移放疗后 2年内 ,常见转移是肺、骨、肝 ,放疗前新辅助化疗和放疗后辅助化疗可减少鼻咽癌远处转移及提高生活质量。Objective To evaluate the clinical feature and treatment of distant metastasis of nasopharyngeal carcinoma.Methods A total of 281 patients with nasopharyngeal carcinoma distant metastasis were analyzed retrospectively.Results The nasopharyngeal carcinoma distant metastasis rate was 20.3%(281/1383),and lung,bone and liver metastasis rates were 42.7%(120/281),32.4%(91/281),21.4%(60/281),respectively.Distant metastasis within 1～2 years after radiotherapy rate was 47.7%(134/281).Conclusions The common distant metastasis of most nasopharyngeal carcinoma distant metastases within 1～2 years after radiotherapy occurs in the lungs,bones and the liver.Neo adjuvant chemotherapy and adjuvant chemotherapy aften radiotherapy are expected to decrease distant metastasis and improve prognosis.

关 键 词：鼻咽癌 远处转移 联合化疗 治疗 

分 类 号：R739.630.5[医药卫生—肿瘤]