肺癌骨转移核素显像分析  

Radionuclide imaging analysis of skeletal metastases from lung cancer

作　　者：侯少洋[1] 张蕾[1] 王建军[1] 

机构地区：[1]广东省农垦中心医院,湛江524002

出　　处：《中国肿瘤临床与康复》2001年第2期74-75,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的　探讨肺癌骨转移患者骨显像的特点及规律。方法　 136例肺癌患者做全身骨核素显像。结果　136例肺癌患者中有 87例骨显像异常 ,结合临床及X线诊断为骨转移 ,骨转移的发生率为 6 3 .97%。其中左肺癌的阳性率为 5 8.33 % ,右肺癌的阳性率为 73 .47%。肺腺癌的阳性率 72 .41% ,肺鳞癌的阳性率为 43 .48% ,腺癌较鳞癌容易发生骨转移 (P <0 .0 5 )。 87例骨转移患者中 81例为多发病灶 (占 93 .1% ) ,6例为单发病灶 (占 6 .9% ) ,每例患者的平均病灶数为 6 .39个。骨转移的部位以胸部为多见 ,其余依次为脊柱、骨盆、肢体和颅骨。伴有区域淋巴结及远处其它器官转移的患者出现骨显像异常的可能显著增多 (P <0 .0 5 ) ,骨转移是否发生与肿瘤原发病灶范围之间的关系未能得到统计学证实。结论　肺癌骨转移发生率很高 ,骨转移的发生有一定的规律及特点 。Objective To evaluate the characteristics of skeletal metastases in lung cancer.Methods 136 patients with lung cancer were examined by radionuclide bone imaging.Results Among them,87 cases were identified as having skeletal metastases.The incidence of bone metastases compared with clinical data and X ray examination was about 63.97%.The incidence of cancer in right lung and left lung were 73.47% and 58.33%,respectively.The incidence of bone metastases varied with different lateral of lung cancer (P<0.01).The incidence of adenocarcinoma (72.41%) was higher than squamous carcinoma(43.48%)(P<0.05).Multiple metastatic lesions accounted for 93.1% (81 cases) and solitary 6.9% (6 cases),with an average of 6.39 loci per patient.The site of bone metastases was commonly seen in the thorax,followed by spine,pelivs,limbs and skull. The incidence of bone metastases increased significantly in the patients with local lymph node and or distal metastases(P<0.05).The relation between skeletal metastases and the size of original tumor remained uncertain.Conclusions Bone imaging should be performed in the patients with lung cancer,for its importance for evaluation of staging and treatment.

关 键 词：肺癌 放射性核素显像 骨转移 诊断 治疗 

分 类 号：R734.2[医药卫生—肿瘤]