微导管在肝癌介入治疗上的应用  

The Application of Microcatheter in Initerventional Therapy of Hepatic Cell Carcinoma

作　　者：晁明[1] 蒋定尧[1] 任志达[1] 方兵[1] 

机构地区：[1]浙江大学医学院附属第二医院放射科,浙江杭州310009

出　　处：《实用放射学杂志》2001年第4期247-249,共3页Journal of Practical Radiology

基　　金：浙江省卫生厅青年科研基金资助项目(编号9632)

摘　　要：目的　探讨微导管在肝癌化疗性栓塞中的作用。方法将４Ｆ～５ＦＹａｓｈｉｒｏ、Ｋｏｕｎｏ亲水超滑导管、５Ｆ牧羊钩导管作为导引导管插入肝总或肝固有动脉及肠系膜上动脉，３Ｆ微导管经导引导管置入肝段或肿瘤滋养动脉施行肝癌化疗性栓塞术。结果本组３５例共行化疗性栓塞５０例次，其中１６例小肝癌行肝段栓塞，１９例非小肝癌但癌灶尚局限者行左／右叶或右叶前、后叶栓塞。随访ｌ～２年生存期分别为１００％、８７．５％及５２．６％、４２．ｌ％。术后肝功能损害轻微，元并发症。结论在小肝癌、非小肝癌但癌灶尚局限者或伴有肝动脉异常迂曲、损伤后狭窄、发育变异的情况下，使用微导管提高栓塞精度对改善疗效和避免并发症具有十分重要的临床应用价值。Objective: To investigate the effect of microcatheter in chemoembolization of HCC. Methods Using 4 - F - 5 - F Yashiro/Kouno and 5 - F Hook catheters as guiding catheter,3 - F microcatheter was put into segmental hepatic artery or tumor feeding artery and chemoembolization was carried out. Results All 35 cases had 50 times chemoembolizations totally, of them, 16 cases with small HCC had segmental TAE and 19 cases with large but localized HCC had right/left hepatic artery or anterio/posterio brtanch of right hepatic artery embolization, 1-2 year survial rates were 100%, 87. 5% and 52. 6%,42. l% respectively after TAE. Liver function damage after TAE was slight and no complications occurred. Conclusion Improving embolization precision by using microcatheter is valuable in the cases with small HCC or large but localized HCC with tortuous hepatic artery,hepatic artery stenosis after injury and variations.

关 键 词：肝癌 介入放射学 栓塞治疗 介入治疗 微导管 栓塞精度 

分 类 号：R735.7[医药卫生—肿瘤] R730.55[医药卫生—临床医学]